Signal Transduction and theRelated DisordersPathophysiology DepartmentShiHeZi Medical College
Signal Transduction and the Related Disorders Pathophysiology Department ShiHeZi Medical College
Basic Concept of Cell Signaling(trans-membranous signaling)The process in which cellsthe extracellular stimuli throughsensemembranous orintracellularreceptors,transduce the signals via intracellular molecules,and thus regulate the biological function of thecells
The process in which cells sense the extracellular stimuli through membranous or intracellular receptors, transduce the signals via intracellular molecules, and thus regulate the biological function of the cells Basic Concept of Cell Signaling (trans-membranous signaling)
Major pathways for cell signalingG-protein-mediated pathwayAdenylate cyclase mediatedpathwayPhospholipasemediated pathwaySmall G-protein-mediated pathwayNon-G-protein-mediated pathwayReceptor tyrosine kinase mediated pathwayReceptor serine/threoninekinase mediated pathwayReceptor guanilate cyclase mediated pathwayIntracellular (unclear)receptor mediatedpathway
G-protein-mediated pathway Adenylate cyclase mediated pathway Phospholipase mediated pathway Small G-protein-mediated pathway Non-G-protein-mediated pathway Receptor tyrosine kinase mediated pathway Receptor serine/threonine kinase mediated pathway Receptor guanilate cyclase mediated pathway Intracellular (unclear) receptor mediated pathway Major pathways for cell signaling
Aberrant Cell Signaling andthe Related Disorders
Aberrant Cell Signaling and the Related Disorders
CYTOPLASMEXTRACELLULARFLUID3Response21TransductionReceptionReceptorActivationofcellularresponsesSignal-transductionpathwaySignalmoleculePlasmamembraneGeneral process fortransmembrane signal transduction
General process for transmembrane signal transduction