《病理生理学》课程教学课件（PPT讲稿）Chapter 2 Disorders Of Water And Electrolyte Metabolism（3/3）

PotassiumBalance andPotassium Imbalancet,ShiHeZiMedicalCollege,Pathophysiology Department,HUST

Potassium Balance and Potassium Imbalance Pathophysiology Department, ShiHeZi Medical College, HUST

IPart

Part Ⅰ

PotassiumBalanceI Content and Distribution ofPotassium in the BodyI Intake and Excretion of Potassium

Potassium Balance Ⅰ Content and Distribution of Potassium in the Body Ⅱ Intake and Excretion of Potassium

Dietary K intakeSerum[K+1round4.5mmol/L70~100mmol/dayECF2%ICFTotal bodyK+K content[K*]160mmol/LExcretion31~57mmol/Kg98%ofthetotalbodyweightbodypotassiumtrivial normallySkinColon10%Moreingested,moreexcretedKidneys>80%Lessingested,lessexcretedNotingested,excretiongoesonContent,distribution,intakeand excretionofK

Dietary K intake 70~100mmol/day ECF 2% Serum [K+ ] round 4.5mmol/L K+ Skin trivial normally Colon 10% Kidneys > 80%  More ingested, more excreted  Less ingested, less excreted  Not ingested, excretion goes on Content, distribution, intake and excretion of K Excretion ICF [K+ ] 160mmol/L 98% of the total body potassium Total body K content 31~57mmol/Kg body weight

I Maintenance of Potassium Homeostasis-DistributionofK+ acrossthecellmembraneandRegulationof renalK+excretion

Ⅲ Maintenance of Potassium Homeostasis —Distribution of K+ across the cell membrane and Regulation of renal K+ excretion