交换酮机理(分两步) ()缩酮的水解 参与下步反应 Eto oEt H OEt Eto Et EtoH C CH H3C CH H3C CH H20来自下步反应 Eto EtoH A EtoH 之H3C-c-cH3 H3C一c一cH3 DOHa OH 参与下步反应 CH 3 H?c CH OOH (接下页)
交换酮机理（分两步） (接下页) (i) 缩酮的水解 参与下步反应 参与下步反应 H + CH3 C H3C EtO OEt CH3 C H3C EtO OEt H CH3 C H3C OEt H2O EtO H3C C CH3 OH2 EtOH EtOH H3C C CH3 OH EtOH CH3 C H3C OH CH3 C H3C O H + 来自下步反应
(接上页 (i)新缩酮的生成 OH OH R—c-R R R R EtOH EtoH 来自上步反应 EtoH OEt - HO H-OEt R H R一c—R R-c—R" L R-C-R' Eto Eto OEt OEt
R C R' O H EtOH R C R' OH EtOH R C R' OH R C R' OEt EtO OEt R C R' OH2 EtO R C － H2O R' EtOH H － H R C R' OEt OEt (ii) 新缩酮的生成 (接上页) 来自上步反应