上游充通大￥ Introduction SHANGHAI JIAO TONG UNIVERSITY Protein:生物功能的主要载体，存在于身体各个组织 >Macromolecules(数千~数十万) >Versatile(组成-结构-功能) >Structure and Function(激素、酶.) 生物合成人胰岛素注射液 诺和灵”R笔芯 NovolinR Penfill 度下，静林注射 3:300周郎单位（笔芯） 3m0 mW支X1支度 Maintain blood sugar at appropriate levels Structure and Crystals of human insulin.I
Introduction Structure and Crystals of human insulin. I Protein: 生物功能的主要载体，存在于身体各个组织 Macromolecules (数千~数十万） Versatile （组成-结构-功能） Structure and Function（激素、酶…） Maintain blood sugar at appropriate levels
上游充通大￥ OUTLINES SHANGHAI JIAO TONG UNIVERSITY 结构单元、聚合方式以及聚合后的形成的结构形态 9000806 Primary Secondary Tertiary Quarternary structure structure structure structure 1.Proteins Are Built from a Repertoire of 20 Amino Acids 2.Primary Structure:Amino Acids Are Linked by Peptide Bonds to Form Polypeptide Chains 3.Secondary Structure:Polypeptide Chains Can Fold into Regular Structures Such As the Alpha Helix,the Beta Sheet,and Turns and Loops
OUTLINES 1. Proteins Are Built from a Repertoire of 20 Amino Acids 2. Primary Structure: Amino Acids Are Linked by Peptide Bonds to Form Polypeptide Chains 3. Secondary Structure: Polypeptide Chains Can Fold into Regular Structures Such As the Alpha Helix, the Beta Sheet, and Turns and Loops 结构单元、聚合方式以及聚合后的形成的结构形态
上游充通大学 OUTLINES SHANGHAI JIAO TONG UNIVERSITY Primary Secondary Tertiary Quarternary structure struc量Ure s量ructure s晋ructure 4.Tertiary Structure:Water-Soluble Proteins Fold into Compact Structures with Nonpolar Cores 5.Quaternary Structure:Polypeptide Chains Can Assemble into Multisubunit Structures 6.The Amino Acid Sequence of a Protein Determines Its Three-Dimensional Structure
OUTLINES 4. Tertiary Structure: Water-Soluble Proteins Fold into Compact Structures with Nonpolar Cores 5. Quaternary Structure: Polypeptide Chains Can Assemble into Multisubunit Structures 6. The Amino Acid Sequence of a Protein Determines Its Three-Dimensional Structure
上游充通大￥ OUTLINES SHANGHAI JIAO TONG UNIVERSITY 结构单元、聚合方式以及聚合后的形成的结构形态 9000e0e Primary Secondary Tertiary Quarternary structure structure structure structure 1.Proteins Are Built from a Repertoire of 20 Amino Acids 2.Primary Structure:Amino Acids Are Linked by Peptide Bonds to Form Polypeptide Chains 3.Secondary Structure:Polypeptide Chains Can Fold into Regular Structures Such As the Alpha Helix,the Beta Sheet,and Turns and Loops
OUTLINES 1. Proteins Are Built from a Repertoire of 20 Amino Acids 2. Primary Structure: Amino Acids Are Linked by Peptide Bonds to Form Polypeptide Chains 3. Secondary Structure: Polypeptide Chains Can Fold into Regular Structures Such As the Alpha Helix, the Beta Sheet, and Turns and Loops 结构单元、聚合方式以及聚合后的形成的结构形态
上游充通大￥ 1.Proteins Are Built from a SHANGHAI JIAO TONG UNIVERSITY Repertoire of 20 Amino Acids Transcription Trarelation 转录 翻译 Protein DNA RNA 蛋白质 Reverse Trarscription 逆转录 Transcription Translation Protein DNA mRNA DNA的结构单元：核苷酸4种 蛋白质的结构单元：氨基酸20种 Versatile (组成结构-功能)
1.Proteins Are Built from a Repertoire of 20 Amino Acids DNA的结构单元： 核苷酸 4 种 蛋白质的结构单元：氨基酸 20 种 Versatile （组成-结构-功能）