上游充通大学 Introduction SHANGHAI JIAO TONG UNIVERSITY 中心法则： 核酸 蛋白质 Transcription Trarelation 转录 翻译 Protein DNA RNA 蛋白质 Reverse Trarscription 逆转录 Transcription Translation Protein DNA mRNA 基因必须表达后才能执行其功能；蛋白质调节基因的表达
Introduction 中心法则： 基因必须表达后才能执行其功能；蛋白质调节基因的表达。 核酸 蛋白质
上游充通大学 OUTLINES SHANGHAI JIAO TONG UNIVERSITY 1.A Nucleic Acid Consists of Four Kinds of Bases Linked to a Sugar-Phosphate Backbone 2.A Pair of Nucleic Acid Chains with Complementary Sequences Can Form a Double- Helical Structure 3.DNA Is Replicated by Polymerases That Take Instructions from Templates
1.A Nucleic Acid Consists of Four Kinds of Bases Linked to a Sugar-Phosphate Backbone 2.A Pair of Nucleic Acid Chains with Complementary Sequences Can Form a DoubleHelical Structure 3.DNA Is Replicated by Polymerases That Take Instructions from Templates OUTLINES
上浒充通大 OUTLINES SHANGHAI JIAO TONG UNIVERSITY 4.Gene Expression Is the Transformation of DNA Information into Functional Molecules 5.Amino Acids Are Encoded by Groups of Three Bases Starting from a Fixed Point 6.Most Eukaryotic Genes Are Mosaics of Introns and Exons
4.Gene Expression Is the Transformation of DNA Information into Functional Molecules 5.Amino Acids Are Encoded by Groups of Three Bases Starting from a Fixed Point 6.Most Eukaryotic Genes Are Mosaics of Introns and Exons OUTLINES
上游充通大兽 1 A Nucleic Acid Consists of 4 Kinds of Bases SHANGHAI JIAO TONG UNIVERSITY Linked to a Sugar-Phosphate Backbone >生物大分子 >携带遗传信息 >核苷酸的线性聚合物 >每个核苷酸有糖基、磷酸和碱基 遗传信息 Basej Basej+1 Basei+2 骨架…》Sugar Sugar Sugar Sugar Sugar ●● Phosphate Phosphate Phosphate Phosphate Phosphate Figure 4.1 Polymeric structure of nucleic acids
1 A Nucleic Acid Consists of 4 Kinds of Bases Linked to a Sugar-Phosphate Backbone Figure 4.1 Polymeric structure of nucleic acids. 生物大分子 携带遗传信息 核苷酸的线性聚合物 每个核苷酸有糖基、磷酸和碱基 骨架 遗传信息
上游充通大学 1 A Nucleic Acid Consists of 4 Kinds of Bases SHANGHAI JIAO TONG UNIVERSITY Linked to a Sugar-Phosphate Backbone 核糖和脱氧核糖： >五元糖 >核糖-mRNA >脱氧核糖-DNA 5 HO OH HO OH H HO OH HO Ribose Deoxyribose Figure 4.2 Ribose and deoxyribose.Atoms in sugar units are numbered with primes to distinguish them from atoms in bases
1 A Nucleic Acid Consists of 4 Kinds of Bases Linked to a Sugar-Phosphate Backbone Figure 4.2 Ribose and deoxyribose. Atoms in sugar units are numbered with primes to distinguish them from atoms in bases. 核糖和脱氧核糖： 五元糖 核糖 --- mRNA 脱氧核糖 --- DNA