基础医学各论Ⅱ Gastrointestinal drugs
基础医学各论II
ANATOMICAL STRUCTURES SURROUNDING THE ABDOMINAL AORTIC ANEURYSM SITE Hepatic, pacreatic and biliary uLcer disorders disorders aBnormal mobility CORONAL VIEW OF ABDOMINAL CAVITY ADAM A D.A.M. Software Inc darcom
Gastrointestinal drugs 1. Drugs used for peptic ulcers 2. Modulators of gastrointestinal functions
Gastrointestinal drugs Peptic ulcers Pathogenesis of Treatment peptic ulcers approaches Infection with gram- Eradicating H. pylori negative Helicobacter infection pylori Increased gastric acid Reducing secretion of secretion gastric acid or neutralizing the acid Inadequate mucosal Protecting the gastric defense against gastric mucosa from damage acid
GASTRIN muscarinIc antagonists RsoH N M K+ K+ YACh C CCK antagonists CCK2l K HIST HIST H+ K M2ECL cell CAMP-dependent ATPase X-proton pump inhibitors AC NSAIDS EP. c pathway parietal cell H+ X-antacids fatty bismuth PGl2 misoprostol metronidazole muscarinIc X-tetracyo antagonists clarithromycin H. pylor 80点 amoxicillin mucus ACh . Sucralfate protection carbonoxolon pirenzepine ACh superficial epithelial cell HCO Mucous Gastric Gastric structure related to peptic ulcer Layer Lumen H7 h 2