Drugs affecting endocrine system Weiwei Hu huwwoziu.edu. cn 88208227 Dept Pharmacology, Medical school Zhejiang University
Drugs affecting endocrine system Weiwei Hu huww@zju.edu.cn 88208227 Dept. Pharmacology, Medical School, Zhejiang University
o Drugs related to adrenocortical hormones n Thyroid hormones and antithyroid drugs D Insulin and oral hypoglycemic drugs
Drugs related to adrenocortical hormones Thyroid hormones and antithyroid drugs Insulin and oral hypoglycemic drugs
oduce ADH and oxytocin Neurosecretory cells produce These hormones move portal These hormones are secreted into a portal system Each type of hypothalamic hormone ether stimulates or When appropriate, ADH and The antenor pituitary secretes axon endings into the bloodstream its hormones into the bloodstream postenor pituitary homone(ADH (FSH and LH) Kidney tubules Ovanes, Testes hormone(GH) oxytocin prolactin(PAL) adrenocortical. tropin(ACTH Smooth muscleMammany in uterus gands 00 Mammary Bones, Tissues Adrenal cortex. Thyroid
Zona Glomerulosa P450 aldo AⅡ Aldosterone K medulla ACTH P450 Zonae Fasciculata/ P45017a Reticularis Cortisol Cortex: adrenocorticoid Androgens Glucocorticoids (Glucocorticosteroids Mineralocorticoids Sex hormones Medulla倒图的线 Medulla: epinephrine norepinepherine
Cortex: adrenocorticoid Glucocorticoids (Glucocorticosteroids) Mineralocorticoids Sex hormones Medulla:epinephrine norepinepherine
Adrenocorticoid n Glucocorticoids hydrocortisone(cortisol), cortisone a Mineralocorticoids: aldosterone, desoxycortone
Adrenocorticoid Glucocorticoids : hydrocortisone (cortisol), cortisone Mineralocorticoids： aldosterone, desoxycortone