A. General properties of ion channels in CVS u Properties of ion channels a Permeation o Selectivity 0 Gating voltage-gatee chemically gated: ligand-gated phospharylation-gated mechanosensitive nongated background /leak channels
A. General properties of ion channels in CVS Properties of ion channels Permeation Selectivity Gating voltage-gated chemically gated: ligand-gated phospharylation-gated mechanosensitive nongated background / leak channels
cR head group on 0=P-0 transmembrane transpor 66000000000
Ion transmembrane transport
Chemically gated Bind ligand Ligand-gated B Phosphorylation- ga Chemically gated Phosphorylate Phosphrylation- gated: G protein/ secona massagers Dephosphorylate Gating mechanisms C Voltage-gated membrane Voltage-gated of ion channels potential D Stretch or pressure- gated Mechanosensitive Stretch
Gating mechanisms of ion channels Chemically gated Ligand-gated Chemically gated Phospharylationgated: G protein / second massagers Voltage-gated Mechanosensitive
A. General properties of ion channels in CVS u Voltage-gated ion channels d Nat channels a Ca2+ channels K+ channels
A. General properties of ion channels in CVS Voltage-gated ion channels Na+ channels Ca2+ channels K+ channels
Outside cell Inside ce‖ filte voltage sensor General structure of ion channels Pore Structure of electivity filter a-subunit
Structure of -subunit General structure of ion channels voltage sensor filter