(3)All the DNA viruses contain contiguous genome.So do most RNA viruses. The genome of some RNA viruses are segmented to reduce the chance of error. Inflenza virus-8 segments,ssRNA genome 16
Inflenza virus-8 segments, ssRNA genome 16 ▶(3) All the DNA viruses contain contiguous genome. So do most RNA viruses. The genome of some RNA viruses are segmented to reduce the chance of error
(4)Gene overlapping.Also found in mitochondria and plasmid DNA. Types of gene overlapping: one gene is completely lies in another gene Partially overlapped Only one base overlapped between two genes 17
17 ▶(4) Gene overlapping. Also found in mitochondria and plasmid DNA. Types of gene overlapping: one gene is completely lies in another gene Partially overlapped Only one base overlapped between two genes
mRNA Viral strand DNA synthesis A'translation beginis here mRNA 中X174 Complementary strand DNA mRNA synthesis Spacer DNA met g少y thr his al由phea 5 met leu leu pro 18
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Discovery of overlapping genes 1977年首先发现的，Sangeri测定了ΦX174核 苷酸序列，ΦX174基因组由5386个核苷酸组 步 。 基因的产物都已被分离，它们所含的氨基酸已 远远超过了5386个核苷酸编码的量，将全部 DNA顺序和蛋白质的氨基酸顺序比较后发现了 重叠基因现象。 19
19 Discovery of overlapping genes • 1977年首先发现的，Sanger测定了фX174核 苷酸序列，фX174基因组由5386个核苷酸组 成。 • 基因的产物都已被分离，它们所含的氨基酸已 远远超过了5386个核苷酸编码的量，将全部 DNA顺序和蛋白质的氨基酸顺序比较后发现了 重叠基因现象
mRNA Vral strand DNA synth港M A translation a一begins here mRNA 争X174 Complementary mRNA strand DNA synthesis Spacer DNA met h his ala phe L LULLL Initiation- met leuleu pro 20
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