Molecular Biology course chater 6 The Biosynthesis f Protein (Translation) chain of amino acids IRNA mRNA odo GG GUU 5 bosom
•Molecular Biology Course Chapter 6 The Biosynthesis of Protein (Translation)
The revised central dogma 基因组的保持 N DNA Replication 閤部介↓ Reverse RNA processing 基因组 RNA 表达 Protein 2025/5
2025/5/15 2 The revised central dogma RNA processing 基 因 组 的 保 持 基 因 组 的 表 达
What is translation? -It is the story about decoding the genetic information contained in messenger RNA(mRNA)into proteins. 2025/5/15 3
2025/5/15 3 What is translation? -It is the story about decoding the genetic information contained in messenger RNA (mRNA) into proteins
Three components of Translation machinery 1. mRNAs (~5%of total cellular RNA) Nucleus 2. tRNAS(~15%) DNA 3. ribosomes (~100 proteins and 3-4 rRNAS-~80%) Protein PROTEIN RN ribosome 4
2025/5/15 4 Three components of Translation machinery 1. mRNAs (~5% of total cellular RNA) 2. tRNAs (~15%) 3. ribosomes (~100 proteins and 3-4 rRNAs-~80%)
Translation extremely costs In rapid growing bacterial cells,protein synthesis consumes ■ 80%of the cell's energy 50%of the cell's dry weight Why? 2025/5/15 5
2025/5/15 5 Translation extremely costs In rapid growing bacterial cells, protein synthesis consumes ◼ 80% of the cell’s energy ◼ 50% of the cell’s dry weight Why?