Molecular Biology course chapter 7 The Control of Gene Expression gene regulatory sequences spacer DNA general transcription factors gene regulatory TATA box upstream stert of promote transcription
Chapter 7 The Control of Gene Expression •Molecular Biology Course
The revised central dogma The structure of DNA 因组的保持 DNA Replication ranscription RNA Translation 基因组的表达 Gene regulation Protein 201
2025/5/15 2 The revised central dogma Gene regulation 基 因 组 的 保 持 基 因 组 的 表 达 The structure of DNA
Outline: Section 1 A brief introduction of gene regulation Section 2 Control of gene expression in Prokaryotes Section 3 Control of gene expression in Eukaryotes 2025/5/15 3
2025/5/15 3 Section 1 A brief introduction of gene regulation Section 2 Control of gene expression in Prokaryotes Section 3 Control of gene expression in Eukaryotes Outline:
Key points: Gene expression,activator,repressor,positive gene regulation,negative gene regulation,signal integration,combinational Control,cis-acting element,.trans-acting factor(基因表达、激活蛋白、 阻遏蛋白、正调控与负调控、信号整合、组合控制、 顺式作用元件、反式作用因子等概念；) Positive and negative control of lac operon; Control mechanism of trp operon; Characteristics and levels of eukaryotic gene regulation,types of DNA binding domains of trans-acting factors(真核基因表达调控特点、层次 等，反式作用因子DNA结合结构域类型。) 2025/5/15
2025/5/15 4 Key points: ◼ Gene expression, activator, repressor, positive gene regulation, negative gene regulation, signal integration, combinational Control, cis-acting element, trans-acting factor (基因表达、激活蛋白、 阻遏蛋白、正调控与负调控、信号整合、组合控制、 顺式作用元件、反式作用因子等概念；) ◼ Positive and negative control of lac operon; ◼ Control mechanism of trp operon; ◼ Characteristics and levels of eukaryotic gene regulation, types of DNA binding domains of trans-acting factors (真核基因表达调控特点、层次 等，反式作用因子DNA结合结构域类型。)
Section 1 A brief introduction of gene regulation 2025/5/15 5
2025/5/15 5 Section 1 A brief introduction of gene regulation