Molecular Biology course Chaptor 6 The biosynthesis of protein (translation) chain of amino acids- Initiation Elongation (Mer Val mRNA CUC EAG AUG GUU Termination Val CGAISTOP GGA AGG GUU LAA nbosome stop codon
•Molecular Biology Course Chaptor 6 The biosynthesis of protein (translation)
The revised central dogma 八NN入八 DNA Replication Transcripti on RNA Translation Protein
The revised central dogma RNA processing
What is translation? -it is the story about decoding the genetic information contained in messenger RNA (mRNA)into proteins
What is translation? -it is the story about decoding the genetic information contained in messenger RNA (mRNA) into proteins
Three components of Translation machinery Nucleus DNA 1.mRNAs (5%of total RNA Transcription cellular RNA); 2.tRNAs(~15%) Protein PROTEIN 3. ribosomes (~100 RN proteins and 3-4 rRNAS-80%) ribosome
Three components of Translation machinery 1. mRNAs (~5% of total cellular RNA); 2. tRNAs (~15%); 3. ribosomes (~100 proteins and 3-4 rRNAs-~80%)
Translation costs extremely In rapid growing bacterial cells,protein synthesis consumes: 80%of the cell's energy; 50%of the cell's dry weight; Why?
Translation costs extremely In rapid growing bacterial cells, protein synthesis consumes: • 80% of the cell’s energy; • 50% of the cell’s dry weight; Why?