心肌氯需↑武供、氣供失平衡 状动脉供血J心肌暂时缺血缺氣 decrease myocardial increase oxygen oxvgen reguirement delivery
心肌氧需 血供、氧供失平衡 冠状动脉供血 心肌暂时缺血缺氧 decrease myocardial oxygen requirement increase oxygen delivery
抗心统痛的头同作用机理 1舒张冠脉,增加心肌氧供血供 2降低心肌耗氧量 舒张静脉降低前负荷 降低心蜜壁张力 扩张小动脉降低后负荷 减慢心率 抑制心肌收缩力 3抗血栓形成
抗心绞痛药的共同作用机理 1.舒张冠脉，增加心肌氧供血供 2.降低心肌耗氧量 舒张静脉降低前负荷 扩张小动脉降低后负荷 减慢心率 抑制心肌收缩力 3.抗血栓形成 降低心室壁张力
DRUGS USED TO TREATANGINA 1。 Nitrates& Nitrites 2.β- blockers 3. Calcium channel blockers 4. Others
1. Nitrates & Nitrites 2. -blockers 3. Calcium channel blockers 4. Others DRUGS USED TO TREAT ANGINA
1. niTRates Nitrites (硝酸酯类及亚硝酸酯类) Nitroglycerin(硝酸甘油) Isosorbide dinitrate(确酸异山梨酯) Isosorbide mononitrate(单硝酸异山梨酯) Amyl nitrite(亚硝酸戊酯) Pentaerythritol(季戊四醇)
1. NITRATES & NITRITES (硝酸酯类及亚硝酸酯类) Nitroglycerin(硝酸甘油) Isosorbide dinitrate(硝酸异山梨酯) Isosorbide mononitrate(单硝酸异山梨酯) Amyl nitrite (亚硝酸戊酯) Pentaerythritol (季戊四醇)
Blood vessel lumen Mechanism of action of Capilary GNOS A Nitric oxide(NO) endotheial nitrates. nitrites cele and other substances in vascular Nitrates NO mALDH,Nitrites smooth muscle rude ce们 SNOs ces。 GC GTP GM、PDE GMP lgh chans Myosin-LC-PO4Myosnc
Mechanism of action of nitrates, nitrites, and other substances in vascular smooth muscle cells