上游充通大￥ SHANGHAI JIAO TONG UNIVERSITY OUTLINES 1.Biochemical Unity Underlies Biological Diversity 2.DNA Illustrates the Interplay between Form and Function 3.Concepts from Chemistry Explain the Properties of Biological Molecules 4.The Genomic Revolution Is Transforming Biochemistry and Medicine
1. Biochemical Unity Underlies Biological Diversity 2. DNA Illustrates the Interplay between Form and Function 3. Concepts from Chemistry Explain the Properties of Biological Molecules 4.The Genomic Revolution Is Transforming Biochemistry and Medicine OUTLINES
上游充通大学 Biological diversity and similarity SHANGHAI JIAO TONG UNIVERSITY Geological and biochemical findings Oxygen atmosphere sunesou! ↓ ↓ ↓ forming ↓ ↓ 4.5 4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5 0.0 Billions of years Key metabolic processes: glucose and oxygen carbon dioxide and water E.Coli human beings Sulfolobus acidicaldarius Arabidopsis thaliana Homo sapiens
Biological diversity and similarity Key metabolic processes： glucose and oxygen carbon dioxide and water E. Coli & human beings Geological and biochemical findings
上游充通大学 SHANGHAI JIAO TONG UNIVERSITY BACTERIA EUKARYA ARCHAEA Carl Woese's discovery in1977. Figure 1.3 The tree of life. Evolutionary paths from a common ancestor to modern organisms can be deduced on the basis of biochemical information
Figure 1.3 The tree of life. Carl Woese‘s discovery in 1977. Evolutionary paths from a common ancestor to modern organisms can be deduced on the basis of biochemical information
上游充通大粤 SHANGHAI JIAO TONG UNIVERSITY Comparing and contrasting details of particular biochemical pathways in different organisms how biological challenges are solved at the biochemical level. In most cases,these challenges are addressed by the adaptation of existing macromolecules 物大分子适应性to new roles rather than by the evolution of entirely new ones. Structure Function
Comparing and contrasting details of particular biochemical pathways in different organisms • how biological challenges are solved at the biochemical level. • In most cases, these challenges are addressed by the adaptation of existing macromolecules 生 物大分子适应性 to new roles rather than by the evolution of entirely new ones. Structure & Function
上游充通大￥ SHANGHAI JIAO TONG UNIVERSITY OUTLINES 1.Biochemical Unity Underlies Biological Diversity 2.DNA Illustrates the Interplay between Form and Function 3.Concepts from Chemistry Explain the Properties of Biological Molecules 4.The Genomic Revolution Is Transforming Biochemistry and Medicine
1. Biochemical Unity Underlies Biological Diversity 2. DNA Illustrates the Interplay between Form and Function 3. Concepts from Chemistry Explain the Properties of Biological Molecules 4.The Genomic Revolution Is Transforming Biochemistry and Medicine OUTLINES