Drugs Used to Treat Epilepsy
Drugs Used to Treat Epilepsy
OVERVIEW OF EPILEPSY Epilepsy is not a single entity;it is a family of different recurrent seizure disorders that have in common the sudden,excessive and disorderly discharge of cerebral neurons
OVERVIEW OF EPILEPSY ◼ Epilepsy is not a single entity; it is a family of different recurrent seizure disorders that have in common the sudden, excessive and disorderly discharge of cerebral neurons
Etiology The neuronal discharge in epilepsy results from the firing of a small population of neurons in some specific area of the brain,referred to as the primary focus. Primary epilepsy Secondary epilepsy
Etiology ◼ The neuronal discharge in epilepsy results from the firing of a small population of neurons in some specific area of the brain, referred to as the primary focus. Primary epilepsy Secondary epilepsy
Classification of epilepsy EPIL三PSY P865 Simple Complex GENERALIZED Tonic-clonle(grand mal) Absence (petit mal) Myoclonic Febrlle selzures In children Status epllepticus Figure 15.2 Classification of epilepsy
Classification of epilepsy
Mechanism of action of antiepileptic drugs Drugs that are effective in seizure reduction can either block the initiation of the electrical discharge from the focal area or,more commonly,prevent the spread of the abnormal electrical discharge to adjacent brain areas
Mechanism of action of antiepileptic drugs ◼ Drugs that are effective in seizure reduction can either block the initiation of the electrical discharge from the focal area or, more commonly, prevent the spread of the abnormal electrical discharge to adjacent brain areas