Antituberculous drug First-line agents: Isoniazid(INH) Rifampin Pyrazinamide Ethambutol Streptomycin
Antituberculous drug First-line agents: Isoniazid(INH) Rifampin Pyrazinamide Ethambutol Streptomycin
Second-line agents Ofloxacin Ciprofloxacin Para-amino salicylic acid Amikacin
Second-line agents : Ofloxacin Ciprofloxacin Para-amino salicylic acid Amikacin
Isoniazid 【Antibacterial action】 1.Isoniazid has narrow antibacterial spectrum 2.It is active against mycobacterium tuberculosis 3.It is bacteriostatic in the stationary phase it is bactericidal in rapidly dividing organisms 3.It is able to penetrate into phagocytic cells
Isoniazid 【Antibacterial action】 1. Isoniazid has narrow antibacterial spectrum 2. It is active against mycobacterium tuberculosis 3. It is bacteriostatic in the stationary phase it is bactericidal in rapidly dividing organisms 3. It is able to penetrate into phagocytic cells
【Mechanism of action】 It inhibits the enzyme responsible for assembly of mycolic acids into the outer layer of the mycobacteria
It inhibits the enzyme responsible for assembly of mycolic acids into the outer layer of the mycobacteria, 【Mechanism of action】
Clinical uses】 It is used for treatment of latent tuberculosis. Usually it combined with other dugs was given to treat tuberculosis
【Clinical uses 】 It is used for treatment of latent tuberculosis. Usually it combined with other dugs was given to treat tuberculosis