ANTIEPILEPTIC DRUGS Phenytoin is effective in suppressing tonic-clonic and partial seizures,and is a drug of choice for initial therapy, particularly in treating adults
ANTIEPILEPTIC DRUGS ◼ Phenytoin is effective in suppressing tonic-clonic and partial seizures, and is a drug of choice for initial therapy, particularly in treating adults
Mechanism of action Phenytoin stabilizes neuronal membranes to depolarization by decreasing the flux of sodium ions in neurons in the resting state or during depolarization.It also reduces the influx of calcium ions during depolarization and suppresses repetitive firing of neurons
Mechanism of action ◼ Phenytoin stabilizes neuronal membranes to depolarization by decreasing the flux of sodium ions in neurons in the resting state or during depolarization. It also reduces the influx of calcium ions during depolarization and suppresses repetitive firing of neurons
