Clinical uses of thyroid hormones 2. Simple goiter(单纯性甲状腺肿) Supply iodide--iodide deficiency Thyroid hormones Surgery--nodule 0 3. Treat after thyroid cancer surgery to reduce tSH level to inhibit recurrence of cancer
2. Simple goiter (单纯性甲状腺肿) Supply iodide--iodide deficiency Thyroid hormones Surgery—nodule 3. Treat after thyroid cancer surgery to reduce TSH level to inhibit recurrence of cancer Clinical uses of thyroid hormones
今CASE42 迟钝 A 44-year-old woman presents to the office because of fatigue. She has felt sluggish for months and thinks she may be anemic. She has started taking iron pills but isn't feeling any better. She has been sleeping well and doesn't feel depressed. She has no- ticed some thinning of her hair and feels as if her skin is dry. She takes a multivitamin and iron supplement, otherwise no medications. She has smoked a pack of cigarettes a day for about 20 years, occasionally drinks alcohol, and doesn't exercise. Her mother takes some kind of thyroid pill and has diabetes. On examination, her blood pressure and pulse are normal. Her hair is thinned but there are no focal patches of alopecia"or scarringof the scalp. Her skin is diffusely dry. Her thyroid gland feels diffusely en larged,is nontender", and has no nodules. The remainder of her exam is unremark able. Lab tests show a normal complete blood count(CBC), glucose, and electro- lytes. Her thyroid-stimulating hormone( TSH) level is elevated, and T, level is re- duced. You diagnose her with hypothyroidismand start her on oral levothyroxineso- dium
迟钝 触痛
Antithyroid drugs
Antithyroid drugs
Hyperthyroidism Graves Disease is the most common cause of hyperthyroidism (60-80%)of all cases Graves disease is caused by an abnormal immune system response that attacks the thyroid gland, and it causes too much roduction of thyroid hormones Antibodies serve as agonists to the TSH receptors on the thyroids surface, causing thyroid growth and activation of hormone synthesis and secretion Females are affected more frequently than men 10: 1.5 Incidence peaks from ages 20-40
Hyperthyroidism Graves Disease is the most common cause of hyperthyroidism (60-80%) of all cases. Graves Disease is caused by an abnormal immune system response that attacks the thyroid gland, and it causes too much production of thyroid hormones. Antibodies serve as agonists to the TSH receptors on the thyroid’s surface, causing thyroid growth and activation of hormone synthesis and secretion. Females are affected more frequently than men 10:1.5 Incidence peaks from ages 20-40