A General properties of ion channels in CVS I Properties of ion channels Permeation Selectivity u Gating voltage-gated chemically gated: ligand-gated 口口口口 cyclic nucleotide-gated mechanosensitive nongated background /leak channels
A. General properties of ion channels in CVS Properties of ion channels Permeation Selectivity Gating voltage-gated chemically gated: ligand-gated cyclic nucleotide -gated mechanosensitive nongated background / leak channels
on transmembrane Phospholipid transpor Extracelular 0000000000 Cytoplasmic
Ion transmembrane transport
Closed Open A Ligand-gated V Bind hgand Extracellular d Cytoplasmic B Phosphorylation gated Gating mechanisms of ion channels Dephosphorylate C Voltage-gated Change D Stretch or pressure- gated Stretch Cytoskeleton
Gating mechanisms of ion channels
A General properties of ion channels in CVS D Voltage-gated ion channels u Nat channels 口Ca2+ channels 囗K+ channels
A. General properties of ion channels in CVS Voltage-gated ion channels Na+ channels Ca2+ channels K+ channels
Voltage sensor c B 234586 l,Ⅳ Structure of SS1-SS2 a-subunit
Structure of α-subunit Voltage sensor