Zone of Inhibition This picture illustrates the effect of penicillin on a fungus. Note the clear ring of inhibition. It was this observation which initiated Fleming’s further studies
Zone of Inhibition This picture illustrates the effect of penicillin on a fungus. Note the clear ring of inhibition. It was this observation which initiated Fleming’s further studies
Howard Florey Australian-born Studied Science & Medicine in Adelaide Awarded Scholarship at Oxford University Returned to England to complete a PhD
Howard Florey Australian-born Studied Science & Medicine in Adelaide Awarded Scholarship at Oxford University Returned to England to complete a PhD
Ernst Chain Of Russian- German descent Graduated in Chemistry and Physiology Left Berlin when Nazi’s came to power Hired by Florey to work on penicillin project
Ernst Chain Of Russian- German descent Graduated in Chemistry and Physiology Left Berlin when Nazi’s came to power Hired by Florey to work on penicillin project
到目前为止，有8000多种抗生素，2/3是 由放线菌（strepomyces）产生的，并 通过化学结构的改造，总共有3万多种半 合成抗生素，它们的分子量为100-1200， 普遍应用的包括半合成和盐类的抗生素 有350多种，其中以青霉素、头孢霉素、 四环素类、氨基糖苷类和大环内脂类
到目前为止，有8000多种抗生素，2/3是 由放线菌（strepomyces）产生的，并 通过化学结构的改造，总共有3万多种半 合成抗生素，它们的分子量为100-1200， 普遍应用的包括半合成和盐类的抗生素 有350多种，其中以青霉素、头孢霉素、 四环素类、氨基糖苷类和大环内脂类
主要抗生素的使用量（Harvey, 1998) 抗生素种类 用量 (kg/year) 动物1996 人类 1997/1998 头孢类 四环类 氨基糖类 大环内酯类 121,603 323,151 37,058 71,222 314,498 47,500 5,409 47,696
主要抗生素的使用量（Harvey, 1998) 抗生素种类 用量 (kg/year) 动物1996 人类 1997/1998 头孢类 四环类 氨基糖类 大环内酯类 121,603 323,151 37,058 71,222 314,498 47,500 5,409 47,696