Representativeoscillation dynamicsof twosibling cellsC8.00062min122min192min242mineoesao6,0004,0002,000060300120180240360Time (min)Comparison of sibling cells showsskippedordelayed peaks(comparefilled andopen circles),whichmightbepartiallyexplainedby uneven distribution of cellularmaterials
Representative oscillation dynamics of two sibling cells Comparison of sibling cells shows skipped or delayed peaks (compare filled and open circles), which might be partially explained by uneven distribution of cellular materials
SugarsFattyacidsGhyceralODEmodelEthanolTCAcycleAcetyi-CoPPPPtatAcsATPCMetabolites(AcCoA,AcP,OAc-,andAcPHOAc)AcADⅡdAcCoAVAcscs -Vpua +Vgly -VTcAHOACdtdAcPVpaHOACOAC-VAckdtdoAc*d-VAck -VAcE -VAcsdtLacI = RLacl Ra,LacidtdHOAcVAcE-VooutdtaPta = Rpa - Ra,PadtProteinsLacl,Ptaand AcsAcs=R.cs -Ra.Acs-Acsdt
ODE model Metabolites (AcCoA, AcP, OAc−, and HOAc) Proteins LacI, Pta, and Acs