2.饲料工业: 甲硫氨酸等必需氨基酸可用于制造动物饲料 3.医药工业: 多种复合氨基酸制剂可通过输液治疗营养或代 谢失调 苯丙氨酸与氮芥子气合成的苯丙氨酸氮芥子气 对骨髓肿瘤治疗有效,且副作用低。 4.化学工业:谷氨基钠作洗涤剂丙氨酸制造丙氨 酸纤维
2. 饲料工业： 甲硫氨酸等必需氨基酸可用于制造动物饲料 3. 医药工业： 多种复合氨基酸制剂可通过输液治疗营养或代 谢失调 苯丙氨酸与氮芥子气合成的苯丙氨酸氮芥子气 对骨髓肿瘤治疗有效,且副作用低。 4. 化学工业：谷氨基钠作洗涤剂,丙氨酸制造丙氨 酸纤维
Introduction Amino acids are used for a variety of purposes Food Industry: Flavor enhancer; Sweetener(Glycine) Chemical Industry: Building blocks of compounds Pharmaceutical Industry: In Infusion; in special dietary food (essential amino acid) Leu, Ile, Lys, Phe, Met, Trp, Val, Thr, Arg, His Animal feed additive: Feedstuff; eg Soybean --methionine
Introduction Amino acids are used for a variety of purposes Food Industry: Flavor enhancer; Sweetener (Glycine) Chemical Industry: Building blocks of compounds Pharmaceutical Industry: In Infusion; in special dietary food (essential amino acid) Animal feed additive: Feedstuff; eg. Soybean -- methionine Leu, Ile, Lys, Phe, Met, Trp, Val, Thr, Arg, His
Tr Introduction The barrel represents the nutritive value of soybean meal Phe which is first limited Met Lys by its Fig 13.3 The barrel represents methionine content the nutritive value of soybean meal, which is first limited by its methionine content LGu
Introduction The barrel represents the nutritive value of soybean meal, which is first limited by its methionine content
Production methods and tools Classical strain development Bacteria do not normally excrete amino acids in significant amounts because regulatory mechanisms control the amino acid synthesis in an economical way. a great number of amino-acid-producing bacteria have been derived by mutagenesis and screening programmes
Production methods and tools Classical strain development: Bacteria do not normally excrete amino acids in significant amounts because regulatory mechanisms control the amino acid synthesis in an economical way. A great number of amino-acid-producing bacteria have been derived by mutagenesis and screening programmes
Production methods and tools Consecutive application: .Undirected mutagenesis; .Selection for a specific phenoty pe . Selection of the mutant with the best aa accumulation
Production methods and tools Consecutive application: •Undirected mutagenesis; •Selection for a specific phenotype; •Selection of the mutant with the best AA accumulation