Chapter22Nucleotidemetabolism.13UNIT V Integration of Metabolism...14Chapter 23 Metabolic effects of insulin and glucagon.....14Chapter 24Thefeed-fast cycle...14...15Chapter25Diabetes mellitus.Chapter26Nutrition....16
Chapter 22 Nucleotide metabolism .13 UNIT V Integration of Metabolism.14 Chapter 23 Metabolic effects of insulin and glucagon.14 Chapter 24 The feed-fast cycle.14 Chapter 25 Diabetes mellitus.15 Chapter 26 Nutrition.16
教学时数分配表72学时）(共 自学实验示教备注教学内容理论1000IntroductionUNIT I: Protein Structure and Function0001Chapter 1 : Amino Acids3000Chapter 2: Structure of Proteins3000Chapter 3: Globular Proteins4000Chapter 4:Enzymes2000Chapter 5: VitaminsUNIT II:Bioenergetics and Carbohydrate Metabolism3000Chapter 6: Bioenergetics1000Chapter 7: Introduction to Carbohydrates0300Chapter 8: Introduction to Metabolism and Glycolysis000Chapter 9: Tricarboxylic Acid Cycle, Pyruvate Dehydrogenase Complex5and oxidative phosphorylation2000Chapter 10: Gluconeogenesis2000Chapter 11: Glycogen Metabolism2000Chapter 12: Metabolism of Monosaccharides and DisaccharidesChapter13:PentosePhosphatePathway andNicotinamide2000AdenineDinucleotidePhosphateChapter 14:Glycosaminoglycans, Proteoglycans, and2000GlycoproteinsUNIT Ill:Lipid Metabolism0010Chapter 15:Dietary Lipids MetabolismChapter 16: Fatty Acid, Ketone Body, and Triacylglycerol5000MetabolismChapter 17: Phospholipid, Glycosphingolipid, and Eicosanoid0400Metabolism4000Chapter 18: Cholesterol, Lipoprotein, and Steroid MetabolismUNIT IV: Nitrogen Metabolism4000Chapter19:AminoAcids:DisposalofNitrogen3000Chapter20:AminoAcidDegradationand Synthesis2000Chapter 21:Conversion of Amino Acids to Specialized Products3000Chapter 22: Nucleotide MetabolismUNIT V: Integration of Metabolism2000Chapter 23: Metabolic Effects of Insulin and Glucagon4000Chapter 24: The Feed-Fast Cycle2000Chapter 25: Diabetes Mellitus2000Chapter 26: Nutrition1
1 教学时数分配表（共 72 学时） 教学内容 理论 自学 实验 示教 备注 Introduction 1 0 0 0 UNIT I: Protein Structure and Function Chapter 1 : Amino Acids 1 0 0 0 Chapter 2: Structure of Proteins 3 0 0 0 Chapter 3: Globular Proteins 3 0 0 0 Chapter 4: Enzymes 4 0 0 0 Chapter 5: Vitamins 2 0 0 0 UNIT II: Bioenergetics and Carbohydrate Metabolism Chapter 6: Bioenergetics 3 0 0 0 Chapter 7: Introduction to Carbohydrates 1 0 0 0 Chapter 8: Introduction to Metabolism and Glycolysis 3 0 0 0 Chapter 9: Tricarboxylic Acid Cycle, Pyruvate Dehydrogenase Complex and oxidative phosphorylation 5 0 0 0 Chapter 10: Gluconeogenesis 2 0 0 0 Chapter 11: Glycogen Metabolism 2 0 0 0 Chapter 12: Metabolism of Monosaccharides and Disaccharides 2 0 0 0 Chapter 13: Pentose Phosphate Pathway and Nicotinamide Adenine Dinucleotide Phosphate 2 0 0 0 Chapter 14: Glycosaminoglycans, Proteoglycans, and Glycoproteins 2 0 0 0 UNIT III: Lipid Metabolism Chapter 15: Dietary Lipids Metabolism 1 0 0 0 Chapter 16: Fatty Acid, Ketone Body, and Triacylglycerol Metabolism 5 0 0 0 Chapter 17: Phospholipid, Glycosphingolipid, and Eicosanoid Metabolism 4 0 0 0 Chapter 18: Cholesterol, Lipoprotein, and Steroid Metabolism 4 0 0 0 UNIT IV: Nitrogen Metabolism Chapter 19: Amino Acids: Disposal of Nitrogen 4 0 0 0 Chapter 20: Amino Acid Degradation and Synthesis 3 0 0 0 Chapter 21 : Conversion of Amino Acids to Specialized Products 2 0 0 0 Chapter 22: Nucleotide Metabolism 3 0 0 0 UNIT V: Integration of Metabolism Chapter 23: Metabolic Effects of Insulin and Glucagon 2 0 0 0 Chapter 24: The Feed-Fast Cycle 4 0 0 0 Chapter 25: Diabetes Mellitus 2 0 0 0 Chapter 26: Nutrition 2 0 0 0
合计72000Appendix: Clinical Case studyI INTEGRATIVE CASES1.1 Chest PainMyocardial infarction, LDL, cholesterol,HMG-CoA, Km1.2Severe Fasting HypoglycemiaGlucose 6-phosphatase deficiency (glycogen storagedisease [GSD]type Ia, von Gierke disease)VitD, purine-urate, triglyceride, membrane protein biosynthesis1.3Hyperglycemia &HyperketonemiaTypeI diabetes,Diabetic ketoacidosisII. FOCUSED CASES2.1 Microcytic AnemiaHb,Anemia withbeta-Thalassemia Minor,allele-specific oligonucleotide(ASO)hybridizationtedlnique useful in the diagnosis,2.6Dark Urine &YellowScleraeGlucose6-phosphatedehydrogenase(G6PD)defliciency,anX-Ilnked disorderthatcauseshemolysis (RBC lysis)2.7Joint painJoint Pain with Gout2.9 Elevated AmmoniaHyperammonemia with a Urea CycleDefectUNITIProteinStructureandFunctionChapter 1 Amino Acids[Aims & Requirements]1.Befamiliarwiththeclassificationof20aminoacids commonlyfound inproteins2.Befamiliar with thefeatures of some specific amino acids3.Understandtheconceptofpl (isoelectricpoint)[Main Contents]1.Overview2.Structureand classification ofAAs3.AcidicandbasicpropertiesofAAs[Key & Difficult Points]Classificationof20aminoacids.Conceptofpl(isoelectricpoint)[Teaching Methods]1.LecturewithMultimedia2.Group discussionChapter 2 Structure of Proteins[Aims&Requirements1.Understand the concepts of peptide bond,peptide unit, denaturation, and renaturation2.Be familiar with the molecular structure of proteins and protein physicochemical properties3. Understand the structure-function relationships of proteins4. Be aware of the concepts ofmotif and domain[Main Contents]1.Overview2
2 合计 72 0 0 0 Appendix: Clinical Case study I. INTEGRATIVE CASES 1.1 Chest Pain Myocardial infarction, LDL, cholesterol, HMG-CoA, Km 1.2 Severe Fasting Hypoglycemia Glucose 6-phosphatase deficiency (glycogen storage disease [GSD] type Ia, von Gierke disease), VitD, purine-urate, triglyceride, membrane protein biosynthesis 1.3 Hyperglycemia & Hyperketonemia Type I diabetes, Diabetic ketoacidosis II. FOCUSED CASES 2.1 Microcytic Anemia Hb, Anemia with beta-Thalassemia Minor, allele-specific oligonucleotide (ASO) hybridization tedlnique useful in the diagnosis, 2.6 Dark Urine & Yellow Sclerae Glucose 6-phosphate dehydrogenase ( G6PD) defliciency, an X·llnked disorder that causes hemolysis (RBC lysis) 2.7 Joint pain Joint Pain with Gout 2.9 Elevated Ammonia Hyperammonemia with a Urea Cycle Defect UNIT I Protein Structure and Function Chapter 1 Amino Acids [Aims & Requirements] 1. Be familiar with the classification of 20 amino acids commonly found in proteins 2. Be familiar with the features of some specific amino acids 3. Understand the concept of pI (isoelectric point) [Main Contents] 1. Overview 2. Structure and classification of AAs 3. Acidic and basic properties of AAs [Key & Difficult Points] Classification of 20 amino acids. Concept of pI (isoelectric point). [Teaching Methods] 1. Lecture with Multimedia 2. Group discussion Chapter 2 Structure of Proteins [Aims & Requirements] 1. Understand the concepts of peptide bond, peptide unit, denaturation, and renaturation 2. Be familiar with the molecular structure of proteins and protein physicochemical properties 3. Understand the structure-function relationships of proteins 4. Be aware of the concepts of motif and domain [Main Contents] 1. Overview