Massachusetts Institute of Technology yE图 Harvard medical school Brigham and women's hospital VA Boston Healthcare System 2.79J/3.96J/BE,441/HST522J FORMATION OF SOFT TISSUE AND BONE AROUND IMPLANTS The Chronic Response to Implants I.V. YannaS, Ph. D and M. spector, Ph D
Massachusetts In Massachusetts Institute of Technology stitute of Technology Harvard Medical School Harvard Medical School Brigham and Wo Brigham and Women’s Hospital men’s Hospital VA Boston Healthcare System VA Boston Healthcare System 2.79J/3.96J/BE.441/HST522J 2.79J/3.96J/BE.441/HST522J FORMATION OF SOFT TISSUE AND BONE FORMATION OF SOFT TISSUE AND BONE AROUND IMPLANTS: AROUND IMPLANTS: The Chronic Response to Implants The Chronic Response to Implants I.V. Yannas, Ph.D. and M. Spector, Ph.D. I.V. Yannas, Ph.D. and M. Spector, Ph.D
RESPONSE TO IMPLANTS WOUND HEALING Surgical Implantation Inc. time ascular Response Acute Clotting Inflammation Phagocytosis Granulation Neovascularization New Collagen Synthesis Tissue Tissue of labile and stable cells Tissue of permanent cells Implant Movement FrameworkFramework scarring Intact Destroved (fibrous encapsulation synovium Regen. scarring Chronic Inflammation (incorp. (fibrous encapsulation; of implant) synovium) hronic inflammation
RESPONSE TO IMPLANTS: RESPONSE TO IMPLANTS: WOUND HEALING WOUND HEALING Surgical Implantation Surgical Implantation Vascular Response Vascular Response Clotting Clotting Phagocytosis Phagocytosis Neovascularization Neovascularization New Collagen Synthesis New Collagen Synthesis Tissue of Labile and Stable Cells Tissue of Labile and Stable Cells Tissue of Permanent Cells Tissue of Permanent Cells Framework Framework Framework Framework Scarring Scarring Intact Destroyed Intact Destroyed (fibrous encapsulation; (fibrous encapsulation; synovium) synovium) Regen. Scarring Scarring Chronic Inflammation Chronic Inflammation (incorp. (fibrous encapsulation; (fibrous encapsulation; of implant) of implant) synovium) synovium) Chronic Inflammation Chronic Inflammation Acute Inflammation Inflammation Granulation Granulation Tissue Imp lant Movement ant Movement Inc. time Inc. time
Photo removed due to copyright considerations I Metchnikoff
Photo removed due to copyright considerations. I. Metchnikoff
In 1923 a piece of glass was removed from a patients back: it had been there for year. It was surrounded by a minimal amount of fibrous tissue, lined by a glistening synovial sac, containing a few drops of clear yellow fluid. Photo removed due to copyright considerations Smith-Peterson J. Bone Jt. Surg 30-B:59(1948)
In 1923 a piece of glass was removed from a patient’s back; it had been there for a year. It was surrounded by a minimal amount of fibrous tissue, lined by a glistening synovial sac, containing a few drops of clear yellow fluid. Photo removed due to copyright considerations. Smith-Peterson J. Bone Jt. Surg., 30-B:59 (1948)
Four pages removed due to copyright considerations I. Silver
Four pages removed due to copyright considerations. I. Silver