北BIOCHEMISTRYANDMOLECULARBIOLOGY2.Overall nitrogen metabolism> Amino acid catabolism is part of the larger processof whole body nitrogen metabolism. Nitrogen entersthe body in a variety of compounds present in the food,the most important being amino acids contained indietary protein.Department ofBiochemistry and Molecular Biology,MedicineSchool
Department of Biochemistry and Molecular Biology, Medicine School BIOCHEMISTRY AND MOLECULAR BIOLOGY ➢ Amino acid catabolism is part of the larger process of whole body nitrogen metabolism. Nitrogen enters the body in a variety of compounds present in the food, the most important being amino acids contained in dietary protein. 2.Overall nitrogen metabolism
Essential amino acidsBeans(richGrains Crich ininlysine)methionine)MilkPastaefagioli (pasta andbeans,ahealthyItaliansouptiff13.mov
Department of Biochemistry and Molecular Biology, Medicine School BIOCHEMISTRY AND MOLECULAR BIOLOGY
BIOCHEMISTRYANDMOLECULARBIOLOGY2.Overall nitrogen metabolism> Nitrogen leaves the body as urea, ammonia, andother products derived from amino acid metabolismThe role of body proteins in these transformationsraises two important concept: the amino acid pooland protein turnover.Department ofBiochemistry and Molecular Biology,MedicineSchool
Department of Biochemistry and Molecular Biology, Medicine School BIOCHEMISTRY AND MOLECULAR BIOLOGY ➢ Nitrogen leaves the body as urea, ammonia, and other products derived from amino acid metabolism. The role of body proteins in these transformations raises two important concept: the amino acid pool and protein turnover. 2.Overall nitrogen metabolism
H2N-C-NH2HUreaAmmoniaUricacidExcreted Forms of Nitrogen
Department of Biochemistry and Molecular Biology, Medicine School BIOCHEMISTRY AND MOLECULAR BIOLOGY
大BIOCHEMISTRYANDMOLECULARBIOLOGY2.Overall nitrogen metabolismA. Amino acid poolAmino acids released by hydrolysis ofdietary or tissue protein mix with other freeamino acids distributed throughout the bodyand collectively constitute the amino acid poolDepartment of Biochemistry and Molecular Biology,MedicineSchool
Department of Biochemistry and Molecular Biology, Medicine School BIOCHEMISTRY AND MOLECULAR BIOLOGY 2.Overall nitrogen metabolism A. Amino acid pool Amino acids released by hydrolysis of dietary or tissue protein mix with other free amino acids distributed throughout the body, and collectively constitute the amino acid pool