BIOCHEMISTRYANDMOLECULARBIOLOGYChapter 32Biosynthesis of ProteinDepartment of Biochemistry and Molecular Biology,Medicine School
Department of Biochemistry and Molecular Biology, Medicine School BIOCHEMISTRY AND MOLECULAR BIOLOGY Chapter 32 Biosynthesis of Protein
ABIOCHEMISTRYANDMOLECULARBIOLOGYOutline*Overview*Substance for protein synthesis*Biosynthesis of Protein*Post-Translational Modification ofPolypeptideChainsDepartment of Biochemistry and Molecular Biology,Medicine School
Department of Biochemistry and Molecular Biology, Medicine School BIOCHEMISTRY AND MOLECULAR BIOLOGY Outline *Overview *Substance for protein synthesis *Biosynthesis of Protein *Post- Translational Modification of Polypeptide Chains
BIOCHEMISTRYANDMOLECULARBIOLOGY1.overviewGeneexpressionDNATemplatestrandTranscriptionmRNAACCodonTranslationProteinMetProAlaLeuArgfaminoacid chain)AlanineMethionineProlineLeucineArginineeSchool
Department of Biochemistry and Molecular Biology, Medicine School BIOCHEMISTRY AND MOLECULAR BIOLOGY 1. overview
XBIOCHEMISTRYANDMOLECULARBIOLOGY2.Substancefor protein synthesis> mRNA----Template for translation>Ribosome--- Place for protein synthesis>tRNA---Transfer amino acid> The other substanceDepartment of Biochemistry and Molecular Biology,Medicine School
Department of Biochemistry and Molecular Biology, Medicine School BIOCHEMISTRY AND MOLECULAR BIOLOGY 2. Substance for protein synthesis ➢ mRNA-Template for translation ➢Ribosome- Place for protein synthesis ➢tRNA-Transfer amino acid ➢ The other substance
BIOCHEMISTRYANDMOLECULARBIOLOGYmRNA----Template for protein synthesisComponent of genetic codon:>Three of nucleotide in mRNA form a genetic codon,one codon represent one amino acid.>Four kinds of nucleotides comprise 64 codons, 61represent amino acid, 3 of them (UAA、UAG、UGA)are termination codonDepartment of Biochemistry and Molecular Biology,Medicine School
Department of Biochemistry and Molecular Biology, Medicine School BIOCHEMISTRY AND MOLECULAR BIOLOGY Component of genetic codon： ➢Three of nucleotide in mRNA form a genetic codon， one codon represent one amino acid. ➢Four kinds of nucleotides comprise 64 codons，61 represent amino acid，3 of them（UAA、UAG、UGA） are termination codon. mRNA-Template for protein synthesis