BIOCHEMISTRYANDMOLECULARBIOLOGYchapter 20The metabolism ofcholesterolDepartment of Biochemistryand Molecular Biology,MedicineSchool
Department of Biochemistry and Molecular Biology, Medicine School BIOCHEMISTRY AND MOLECULAR BIOLOGY chapter 20 The metabolism of cholesterol
ABIOCHEMISTRYANDMOLECULARBIOLOGYOutlineKmetabolism of cholesterolOverviewStructureof cholesterolSynthesis of cholesterolDegradationofcholesterol*Metabolismof bileacidsFunction of bile acidsDepartment of Biochemistry and Molecular Biology,Medicine School
Department of Biochemistry and Molecular Biology, Medicine School BIOCHEMISTRY AND MOLECULAR BIOLOGY Outline * metabolism of cholesterol ✓ Overview ✓ Structure of cholesterol ✓ Synthesis of cholesterol ✓ Degradation of cholesterol *Metabolism of bile acids ✓ Function of bile acids
BIOCHEMISTRYANDMOLECULARBIOLOGY1.metabolism of cholesterolThesynthesis ofcholesterolThe degradation of cholesterolDepartment of Biochemistry and Molecular Biology,Medicine School
Department of Biochemistry and Molecular Biology, Medicine School BIOCHEMISTRY AND MOLECULAR BIOLOGY The synthesis of cholesterol The degradation of cholesterol 1. metabolism of cholesterol
BIOCHEMISTRYANDMOLECULARBIOLOGY1)overviewandinplasmaCholesterol is presentintissueslipoproteins either as free cholesterol or, combined with along-chain fatty acid, as cholesteryl esterDepartment of Biochemistry and Molecular Biology,Medicine School
Department of Biochemistry and Molecular Biology, Medicine School BIOCHEMISTRY AND MOLECULAR BIOLOGY Cholesterol is present in tissues and in plasma lipoproteins either as free cholesterol or, combined with a long-chain fatty acid, as cholesteryl ester. 1) overview
BIOCHEMISTRYANDMOLECULARBIOLOGY2)Structureofcholesterol2221202623181217242511162713191415928107HO3546Department of Biochemistry and Molecular Biology,Medicine School
Department of Biochemistry and Molecular Biology, Medicine School BIOCHEMISTRY AND MOLECULAR BIOLOGY HO 1 2 3 4 5 6 7 8 9 10 11 19 12 13 14 15 16 17 18 20 21 22 23 24 25 26 27 2) Structure of cholesterol