Antiarrhythmic Drugs
Antiarrhythmic Drugs
Arrhythmias,disturbancesoftherhythmoftheheart.are conceptually simple-dysfunctions cause abnormalitiesin impulse formation and conduction in the myocardiumArrhythmias can reduce cardiac outputarrhythmias can show a variety of symptoms
Arrhythmias, disturbances of the rhythm of the heart, are conceptually simple-dysfunctions cause abnormalities in impulse formation and conduction in the myocardium. Arrhythmias can reduce cardiac output. arrhythmias can show a variety of symptoms
()to beattoo slowly:sinus bradycardia(2) to beat too rapidly :sinus or ventricular tachycardia.atrial or ventricular premature depolarizationatrial flutter.3) To respond to impulses originatingfrom sites otherthanthe SAnode(4) To respond to impulses traveling alongaccessorypathways that lead to deviant depolarizationA-VreentryWolff-parkinson White syndrome
(1) to beat too slowly : sinus bradycardia (2) to beat too rapidly : sinus or ventricular tachycardia. atrial or ventricular premature depolarization. atrial flutter. (3) To respond to impulses originating from sites other than the SA node (4)To respond to impulses traveling along accessory pathways that lead to deviant depolarization A-V reentry Wolff-parkinson White syndrome
causes of leading to arrhythmias1. Myocardial ischemia2. Coronary artery becomes occludedsuch as in atherosclerosis3. Accumulation of endogenous biological mediatorsuch as potassium, cAMP, thromboxane A2, freeradicals4. Reperfusion after coronary occlusion is necessaryfor tissue recovery and prevention of infarction, butspontaneous resumption of coronary flow is oftenitself a cause of arrhythmias
causes of leading to arrhythmias 1. Myocardial ischemia 2. Coronary artery becomes occluded such as in atherosclerosis 3. Accumulation of endogenous biological mediator such as potassium, cAMP, thromboxane A2 , free radicals 4. Reperfusion after coronary occlusion is necessary for tissue recovery and prevention of infarction, but spontaneous resumption of coronary flow is often itself a cause of arrhythmias
Classification ofarrhythmiasArrhythmias have been defined according to theirappearance on the electrocardiogram （ECG) by theLambeth conventionsBradycardiaSinus bradycardiaA-V conduction blockadearrhythmiasVentricular premature beats,Tachycardia,fibrillationAtrialprematurebeats,tachycardia,flutter and fibrillation
Classification of arrhythmias Arrhythmias have been defined according to their appearance on the electrocardiogram ( ECG ) by the Lambeth conventions. arrhythmias Bradycardia Sinus bradycardia A-V conduction blockade Ventricular premature beats, Tachycardia, fibrillation Atrial premature beats, tachycardia, flutter and fibrillation