Antifungal agents Amphotercin B(两性霉素B) Flucytosine(氟胞嘧啶) Ketoconazole(酮康唑) Fluconazol(氟康唑 Itraconazole(伊曲康唑)
Antifungal agents Amphotercin B（两性霉素B） Flucytosine（氟胞嘧啶) Ketoconazole（酮康唑） Fluconazol（氟康唑） Itraconazole (伊曲康唑）
Inside ns Mechanism of action Pore formed by drug 1.Inhibit the synthesis of ergosterol in fungal Unga ell membrane, cause the leakage of intracellular substances Outside 2.Promotes the penetration of other antifungal agents( ergosterol 两性霉素B) 疏水端物地如(亲水端)
Mechanism of action： 1. Inhibit the synthesis of ergosterol in fungal membrane, cause the leakage of intracellular substances 2.Promotes the penetration of other antifungal agents ( 两性霉素B) （疏水端） （亲水端）
Action mechanisms of antibiotics 1. Inhibit synthesis of bacterial cell walls 2. Affect permeability of cell membrane and lead to leakage of intracellular compounds 3. Inhibit protein synthesis 4. Affect bacterial nucleic acid metabolism 5. Block essential enzymes of folate metabolism
1. Inhibit synthesis of bacterial cell walls 2. Affect permeability of cell membrane and lead to leakage of intracellular compounds 3. Inhibit protein synthesis 4. Affect bacterial nucleic acid metabolism 5. Block essential enzymes of folate metabolism Action mechanisms of antibiotics
抑制细胞壁合成 (青霉素、头孢霉素、万古霉素) 对氦苯甲酸影响叶酸代谢 (磺胺类) 抑制DNA合成 (喹诺酮类) 二氢蝶酸 影响蛋白质合成 全过程抑制 四氢叶酸 (氨基糖苷类) 影响RNA合成 (利福霉素类) 墨墨 30s亚基抑制 四环素类、大观霉素) 5s亚基抑制 影响细胞膜通透性 (红霉素、氯霉素、克林霉素) (多粘菌素、制霉菌素、两性霉素B) 大环内酯类 Action mechanisms of antibiotics
Action mechanisms of antibiotics 大环内酯类
B-Lactam antibiotics other inhibitors of cell wall synthesis
β-Lactam antibiotics & other inhibitors of cell wall synthesis