Muscarinic receptor agonists
Muscarinic receptor agonists
A Muscarinic receptor agonists 口1。 Choline esters碱酯类) 口 Acetylcholine乙酰胆碱 口 Carbachol卡巴胆碱 口 Methacholine醋甲胆碱 口 Bethanechol chloride氯贝胆碱 口2. Natural alkaloids(性物碱类) 口 Pilocarpine毛果芸香碱(匹罗卡品) 口 Muscarine毒_
A Muscarinic receptor agonists 1. Choline esters (胆碱酯类) Acetylcholine 乙酰胆碱 Carbachol 卡巴胆碱 Methacholine 醋甲胆碱 Bethanechol chloride 氯贝胆碱 2. Natural alkaloids (生物碱类) Pilocarpine 毛果芸香碱（匹罗卡品） Muscarine 毒蕈碱
Muscarinic receptor agonists Pilocarpine毛果芸香碱(匹罗卡品) Hs c2 CH2 CH3 Pilocarpine毛果芸香碱
Pilocarpine 毛果芸香碱（匹罗卡品） O N O H5C2 CH2 CH3 H3C H3C H3C N CH2CH2OCOCH3 + ? Pilocarpine 毛果芸香碱 Muscarinic receptor agonists
Muscarinic receptor agonists u 1. Pharmacological effects o(1)Eyes Miosis(缩瞳): contraction of sphincter muscle of iris u Lowing intraocular pressure(降低眼内压): enlarging angle of anterior chamber, increasing drainage of aquous humor Spasm of accommodation(调节癌挛): contraction of ciliary muscle, contraction for near vISIon
1. Pharmacological effects （1）Eyes Miosis（缩瞳）: contraction of sphincter muscle of iris Lowing intraocular pressure（降低眼内压）: enlarging angle of anterior chamber, increasing drainage of aquous humor Spasm of accommodation（调节痉挛）: contraction of ciliary muscle, contraction for near vision Muscarinic receptor agonists
Cornea Iris, cilliary Circular fibers muscles, and (Sphincter, M Lens TIS Schelemm canal Radial fibers Suspensory (Dilator, a) ligaments Circular fibers Ciliary muscles (M Medional fibers Schlemm can Aqueous humor (8) scle
Iris, cilliary muscles, and Schelemm canal