ATP produced from citric acid cycleAcetylCoACitrateOxaloacetateIsocitrateTNAD+CO2MalateNAD+α-KetoglutarateFumarateNAD+CCO2SuccinateproducesSuccinylCoA★FADNADHandFADHFADH2NADH1/202leadtoADPOxidativephosphorylationATPFormationofH20ATPFADHNAD+
ATP produced from citric acid cycle
NADHandFADH2produceATPthrouthoxidativephosphorylationMITOCHONDRIONInnermembraneADP+POutermembraneATPComplexV(F,domain)IntermembraneMatrixspaceNAD+11202H0ATPIADPMITOCHONDRIALNADHtransporterMATRIXComplexVElectronflow(Fodomain)ComplexcomplexcomplexINTERMEMBRANESPACEADPATPBioenergeticsandoxidativephosphorylation
NADH and FADH2 produce ATP throuth oxidative phosphorylation Bioenergetics and oxidative phosphorylation
BIOCHEMISTRYANDMOLECULARBIOLOGYQuestions1. What happened in the TCA cycle?2. How many ATPs would be produced in one cycle?Department of Biochemistry and Molecular Biology,Medicine School
Department of Biochemistry and Molecular Biology, Medicine School BIOCHEMISTRY AND MOLECULAR BIOLOGY Questions 1. What happened in the TCA cycle? 2. How many ATPs would be produced in one cycle?
BIOCHEMISTRYANDMOLECULARBIOLOGYOutlineOverviewReactions of the TCA CycleEnergyproductionRegulation of theTCACycleDepartment of Biochemistryand MolecularBiology,Medicine School
Department of Biochemistry and Molecular Biology, Medicine School BIOCHEMISTRY AND MOLECULAR BIOLOGY ➢ Overview ➢ Reactions of the TCA Cycle ➢ Energy production ➢ Regulation of the TCA Cycle Outline
ABIOCHEMISTRYANDMOLECULARBIOLOGYGlucoseAcetyl CoA口OxaloacetateCITRICACIDCYCLEDepartment of Biochemistry and Molecular Biology,Medicine School
Department of Biochemistry and Molecular Biology, Medicine School BIOCHEMISTRY AND MOLECULAR BIOLOGY Glucose