Chapter 13 DNA replication 清苇大当
Chapter 13 DNA replication
13.1 Introduction 13.2 DNA polymerases are the enzymes that make DNA 13.3 DNA synthesis is semidiscontinuous 13.4 Coordinating synthesis of the lagging and leading strands 13.5 The replication apparatus of phage T4 13.6 Creating the replication forks at an origin 13.7 Common events in priming replication at the origin 13.8 Does methylation at the origin regulate initiation? 13.9 Licensing factor controls eukaryotic rereplication 清菜大当
13.1 Introduction 13.2 DNA polymerases are the enzymes that make DNA 13.3 DNA synthesis is semidiscontinuous 13.4 Coordinating synthesis of the lagging and leading strands 13.5 The replication apparatus of phage T4 13.6 Creating the replication forks at an origin 13.7 Common events in priming replication at the origin 13.8 Does methylation at the origin regulate initiation? 13.9 Licensing factor controls eukaryotic rereplication
13.1 Introduction Replisome is the multiprotein structure that assembles at the bacterial replicating fork to undertake synthesis of DNA.Contains DNA polymerase and other enzymes 清苇大当
Replisome is the multiprotein structure that assembles at the bacterial replicating fork to undertake synthesis of DNA. Contains DNA polymerase and other enzymes. 13.1 Introduction
13.2 DNA polymerases are the enzymes that make DNA DNA polymerases are enzymes that synthesize a daughter strand(s)of DNA (under direction from a DNA template).May be involved in repair or replication. DNA replicase is a DNA-synthesizing enzyme required specifically for replication. Repair of damaged DNA can take place by repair synthesis,when a strand that has been damaged is excised and replaced by the synthesis of a new stretch.It can also take place by recombination reactions,when the duplexregion containing the damaged is replaced by an undamaged region from another copy of the genome. Replication of duplex DNA takes place by synthesis of two new strands that are complementary to the parental strands.The parental duplex is replaced by two identical daughter duplexes,each of which has one parental strand and one newly synthesized strand.It is called semiconservative because the conserved units are the single strands of the parental duplex. 情菜大学
DNA polymerases are enzymes that synthesize a daughter strand(s) of DNA (under direction from a DNA template). May be involved in repair or replication. DNA replicase is a DNA-synthesizing enzyme required specifically for replication. Repair of damaged DNA can take place by repair synthesis, when a strand that has been damaged is excised and replaced by the synthesis of a new stretch. It can also take place by recombination reactions, when the duplex region containing the damaged is replaced by an undamaged region from another copy of the genome. Replication of duplex DNA takes place by synthesis of two new strands that are complementary to the parental strands. The parental duplex is replaced by two identical daughter duplexes, each of which has one parental strand and one newly synthesized strand. It is called semiconservative because the conserved units are the single strands of the parental duplex. 13.2 DNA polymerases are the enzymes that make DNA
13.2 DNA polymerases are the enzymes that make 5'■ DNA 3' 都8PB88的2 5 Figure 13.1 Semiconservative 3 replication synthesizes two new strands of DNA 清菜大当
Figure 13.1 Semiconservative replication synthesizes two new strands of DNA. 13.2 DNA polymerases are the enzymes that make DNA