Adrenomimetic drugsadrenoceptoragonistsZhuling（朱玲）
Adrenomimetic drugs adrenoceptor agonists Zhu ling (朱玲)
AdrenomimeticdrugsadrenoceptoragonistsA kind of drugs that mimic the actions(amine) ofand the chemistry structureepinephrine or norepinephrine.Because the action similar tosympathetic effects that stimulation aremediated byreleaseof norepinephrinesympathomimetic drugs
Adrenomimetic drugs adrenoceptor agonists ⚫ A kind of drugs that mimic the actions and the chemistry structure （amine） of epinephrine or norepinephrine. ⚫ Because the action similar to sympathetic effects that stimulation are mediated by release of norepinephrine sympathomimetic drugs
AdrenomimeticdrugsadrenoceptoragonistsDrugsGroupsαR agonistα α Ragonistnoradrenalin metaraminolα Ragonistmethoxamineclonidineα,R agonistβ R agonistisoprenalineβr β, R agonistβ, R agonistdobutaminesalbutamolβ, R agonistaβR agonistadrenalineephedrineDopamineαβDAR agonist
Adrenomimetic drugs adrenoceptor agonists Groups Drugs αR agonist α1 α2 R agonist noradrenalin metaraminol α1 R agonist methoxamine α2R agonist clonidine β R agonist β1 β2 R agonist isoprenaline β1 R agonist β2 R agonist dobutamine salbutamol αβR agonist adrenaline ephedrine αβDAR agonist Dopamine
blood vessels of skin, gutareceptor:contractsheart functionenhancementβ,receptor:β,receptor:bronchial smooth muscles: relaxationskeletalmuscle vessels: relaxationcoronary artery: relaxation
αreceptor： blood vessels of skin, gut contracts β1 receptor：heart function enhancement β2 receptor： bronchial smooth muscles: relaxation skeletal muscle vessels: relaxation coronary artery: relaxation
Adrenomimetic drugsadrenoceptor agonistsCommonnessBasic structure :β--phenylethylaminemain effects in the cadiovascularsystermelimination from uptake, MAO, COMTshockmain application:
Adrenomimetic drugs adrenoceptor agonists Commonness 1 Basic structure :β-phenylethylamine 2 main effects in the cadiovascular systerm 3 elimination from uptake, MAO, COMT 4 main application: shock