Amantadine and rimantadine 【Antiviral actions】 1.Antiviral spectrum They are effective against RNA virus influenza A virus 2.Mechanism: Block the viral membrane matrix protein,M2 Interfere with the release of new virions
【 Antiviral actions】 1. Antiviral spectrum : They are effective against RNA virus influenza A virus 2. Mechanism: Block the viral membrane matrix protein, M2 Interfere with the release of new virions Amantadine and rimantadine
【Clinical uses and adverse effect】 1.It is used for treatment of influenza A infection 2.Amantadine:CNS reaction insomnia,dizziness,ataxia,hallucinations,seizures 3.Contraindications: psychiatric problems,cerebral atherosclerosis, epilepsy;pregnant and nursing mothers
【Clinical uses and adverse effect 】 1. It is used for treatment of influenza A infection 2. Amantadine: CNS reaction insomnia, dizziness, ataxia, hallucinations, seizures 3. Contraindications: psychiatric problems, cerebral atherosclerosis, epilepsy; pregnant and nursing mothers
Ribavirin 【Antiviral actions】 1.Antiviral spectrum: Ribavirin is effective against a broad spectrum of RNA and DNA viruses RSV,hepatitis A virus,influenza A and B 2.Mechanism: Inhibiting viral mRNA synthesis
Ribavirin 【 Antiviral actions】 1. Antiviral spectrum: Ribavirin is effective against a broad spectrum of RNA and DNA viruses RSV, hepatitis A virus, influenza A and B 2. Mechanism: Inhibiting viral mRNA synthesis
【Clinical uses】 1.Ribavirin is used in treating infants and young children infected with severe RSV. 2.It is also used to treat acute hepatitis A virus and influenza A and B infections. 3.Ribavirin may reduce the mortality and viremia of Lassa fever
1. Ribavirin is used in treating infants and young children infected with severe RSV. 2. It is also used to treat acute hepatitis A virus and influenza A and B infections . 3. Ribavirin may reduce the mortality and viremia of Lassa fever. 【Clinical uses 】
【Adverse effect】 Transient anemia,elevated bilirubin. Ribavirin is contraindicated in pregnancy
【Adverse effect】 Transient anemia, elevated bilirubin. Ribavirin is contraindicated in pregnancy