Polyhydroxyalkanoates(PHa) Mostly hydrophobic · Chiral monomers Great structure variety ° Among PHA2 polyhydroxybutyrate is the most common d. Molecular weights range from 10.000 to several millions
• Mostly hydrophobic • Chiral monomers • Great structure variety • Among PHA, polyhydroxybutyrate is the most common • Molecular weights range from 10,000 to several millions Polyhydroxyalkanoates (PHA)
Applications ofPa Biodegradability Biomaterials and Biocompatibility Tissue engineering Hydrophobicity Biodegradable Packaging Gas impermeability Piezoelectroci Electronic Materials Optical activity pecial Properties caused by functional Groups Smart materials?
Applications of PHA • Biodegradability • Biocompatibility • Hydrophobicity • Gas impermeability • Piezoelectrocity • Optical activity • Special Properties caused by functional Groups Biomaterials and Tissue engineering Biodegradable Packaging Electronic Materials ? Smart materials?
PHA Common structure PHA molecular structure O -[CH(CH2)m-C--OI R m=1.2 or 3, R is variable
PHA Common Structure PHA molecular structure —[CH—(CH2 )m—C—O]n—— R O m=1, 2 or 3，R is variable
Commercialized pha [CH-CH2--C-OIn R-Methyl, PHA=Polyhydroxy butyrate(PHB) CH First generation of pha -[CH--CH2--C--On R=Ethyl, Pha-Polyhydroxy valerate(PHv [CH-CH2--C--Ola-[CH--CH2--C--O]b- CHs Second generation of phas PHBV
Commercialized PHA —[CH—CH2—C—O]n— O CH3 R=Methyl，PHA=Polyhydroxybutyrate(PHB) —[CH—CH2—C—O]n— C2H5 O R=Ethyl，PHA=Polyhydroxyvalerate (PHV) —[CH—CH2—C—O]a——[CH—CH2—C—O]b— O O CH3 C2H5 First Generation of PHA Second Generation of PHA: PHBV
Third generation of pha -[CH--CH2C--OaCH-CH2--C--OJh CH CHa Copolymers of 3-hydroxybutyrate and 3-hydroxyhexanoate Copolymers of 3-hydroxybutyrate and 3-hydroxyoctanoate Have been synthesized by doi, steinbuchel and P&g
Third Generation of PHA —[CH—CH2—C—O]a——[CH—CH2—C—O]b— O O CH3 C3H5 Copolymers of 3-hydroxybutyrate and 3-hydroxyhexanoate, Copolymers of 3-hydroxybutyrate and 3-hydroxyoctanoate Have been synthesized by Doi, Steinbuchel and P&G