Industrial Microbiology and Fermentation Technology Textbook: Biology of Microorganisms Seventh edition By Thomas D. Brock et al. (1996) Websitehttp://www.prenhall.com/brock Lecturer: CHEN GUO- Qiang(陈国强) microbes(@public3bta.net.cn Tel: 62783844. Room 102. School of Life sciences
Industrial Microbiology and Fermentation Technology Textbook: Biology of Microorganisms Seventh Edition By Thomas D. Brock et al. (1996) Website: http://www.prenhall.com/~brock Lecturer: CHEN Guo-Qiang (陈国强) microbes@public3.bta.net.cn Tel: 62783844, Room 102, School of Life Sciences
Industrial microbiology and Fermentation Technology Industrial Microbiology is the discipline that uses microorganisms, usually grown on a large scale to produce valuable commercial products or carry out important chemical transformations Fermentation Technology is the technology to grow cells in a large scale with high efficiency, it also includes product recovery processes
Industrial Microbiology and Fermentation Technology • Industrial Microbiology is the discipline that uses microorganisms, usually grown on a large scale, to produce valuable commercial products or carry out important chemical transformations. • Fermentation Technology is the technology to grow cells in a large scale with high efficiency, it also includes product recovery processes
Microbial products: microbial cells, enzymes, pharmaceutical products Specialty chemicals and food additives Cells Bioconversion Products from cells Substrate 00 Enzymes (for example (for example glucose 08.880>cells citic acid) Isomerase Antibiotics Alcohol (for exampl (ethanol) Product Yeast Food cells (for example, additives steroid bioconversions amino acos
Microbial products: microbial cells, enzymes, pharmaceutical products Specialty Chemicals and food additives
Flowsheet for developing an industrial microbial fermentation process Strain selection Laboratory process development Pilot Scale up Industrial Scale up Downstream process development Product packaging techniques Other commercial consideration Examples
Flowsheet for developing an industrial microbial fermentation process • Strain selection • Laboratory process development • Pilot Scale up • Industrial Scale up • Downstream process development • Product packaging techniques • Other commercial consideration • Examples
Strain selection Purchase from Culture collections -Screening of nature circumstances enetic engineering Mutations Cell biology techniques
Strain Selection –Purchase from Culture Collections –Screening of nature circumstances –Genetic engineering –Mutations –Cell biology techniques