Proofreading: DNa polymease III has 325 exonuclease activity G A C丰G C主G G主C G主c Abnormal bonding Mismatched bonding nucleotide DNA polymerase ll 4. 3
Proofreading: DNA polymease III has 3’ 5’ exonuclease activity
nC DNA Replication of Linear Genetic Elements: Protein primer and Telomerase RNA tem lined to 5
Replication of Linear Genetic Elements:Protein Primer and Telomerase
Questions on DNA replication Describe the DNA replication process What proteins are involved in initiation of DNA synthesis Dna replication fork)? How do leading-and lagging strands replicate? What are enzymes involved in replicating the lagging strand? What are the differences between replicating circular dna and linear dna
Questions on DNA replication Describe the DNA replication process. What proteins are involved in initiation of DNA synthesis (DNA replication fork)? How do leading- and lagging strands replicate? What are enzymes involved in replicating the lagging strand? What are the differences between replicating circular DNA and linear DNA
RNA Structure and Function? RNA acts at two levels: Genetic and Functional Genetically: carry the genetic information from DNA Functionally: Structural role Messenger RNA (mRNA) RibosomaIrna (rrNa) Transfer RNA(tRNA) Catalytic RNA: Ribozyme
RNA Structure and Function? RNA acts at two levels: Genetic and Functional: Genetically: carry the genetic information from DNA; Functionally: Structural role • Messenger RNA (mRNA) • Ribosomal RNA (rRNA) • Transfer RNA (tRNA) • Catalytic RNA: Ribozyme