Bacteria enetics Exchange of Genetic Information DiQu(瞿涤) MOH&MOE Key Lab of Medical Molecular Virology Shanghai Medical College, Fudan University 复旦大学基础医学院 医学分子病毒学教育部卫生部重卢实验室 Chapter 7
Bacteria Genetics & Exchange of Genetic Information Shibo Jiang (姜世勃) MOH&MOE Key Lab of Medical Molecular Virology Shanghai Medical College, Fudan University 复旦大学上海医学院分子病毒学教育部/卫生部重点实验室 Di Qu (瞿涤) MOH&MOE Key Lab of Medical Molecular Virology Shanghai Medical College, Fudan University 复旦大学基础医学院 医学分子病毒学教育部/卫生部重点实验室 Chapter 7
Key words Chromsome Plasmid Transposable genetic Elements Phage Lysophage(temperate), virulent phage prophage, lysogen /lysogeny Horizontal gene transfer Transformation transduction General transduction Lysogenic( specific) transduction/conversion Conjugation(transfer of genetic material between bacterial cells by direct cell-to-cell contact or by a bridge-like connection between two cells) F factor, Hfr, R plasmid
Key Words Chromsome Plasmid Transposable Genetic Elements Phage -Lysophage (temperate), virulent phage prophage, lysogen /lysogeny Horizontal Gene transfer Transformation Transduction General transduction Lysogenic （specific）transduction/conversion Conjugation (transfer of genetic material between bacterial cells by direct cell-to-cell contact or by a bridge-like connection between two cells) F factor，Hfr， R plasmid
Copyright o The McGraw-Hill Companies, Inc. Permission required for reproduction or display O-O DNA DNA Duplicate of original molecule Transcription All organisms have dna and rna as genetic material RNA All organisms use the same Translation nucleotides All organisms replicate, transcribe and translate dna Protein The central dogma of molecular biology
The central dogma of molecular biology All organisms have DNA and RNA as genetic material All organisms use the same nucleotides All organisms replicate, transcribe and translate DNA
Growth of bacteria Bacterial Multiplication- Binary Division Cell wall Cell membrane Elongated nucleoid Nucleoid divides: Chromosome(ds dNA) cell wall and membrane begin to form number doubled transverse septum Plasmid( ds DNA) Transverse septum number becomes complete Daughter cells separate
Growth of bacteria Bacterial Multiplication - Binary Division Chromosome (ds DNA) number doubled Plasmid (ds DNA) number ?
General characteristics of bacterial genetics Bacterial dna can be altered by mutations Mutations can result in changes in proteins New traits diversity acquisition of (antibiotics)resistance New traits can be transmitted to daughter cells other microbes Horizontal Gene transfer)
General characteristics of bacterial genetics Bacterial DNA can be altered by mutations Mutations can result in changes in proteins - New traits -diversity -acquisition of (antibiotics) resistance New traits can be transmitted to -daughter cells -other microbes （Horizontal Gene transfer）