扩张型心肌病Idiopathic Dilated CardiomyopathyIDC
扩张型心肌病 Idiopathic Dilated Cardiomyopathy IDC
IDC - DefinitionJ al disease of unknown etiology that principally affectsthe myocardium LV dilatation and systolic dysfunctionpathologyincreased heart size and weightventricular dilatation, normal wall thicknessheart dysfunction out of portion to fibrosis
IDC - Definition ▪ a disease of unknown etiology that principally affects the myocardium ▪ LV dilatation and systolic dysfunction ▪ pathology ➢ increased heart size and weight ➢ ventricular dilatation, normal wall thickness ➢ heart dysfunction out of portion to fibrosis
病因1病毒感染；2）基因及自身免疫（发现本病与组织相容性有关）；3）遗传，代谢，中毒等
病因 1）病毒感染； 2）基因及自身免疫（发现本病与组织相容性有 关）； 3）遗传，代谢，中毒等
Incidence and Prognosis3-10 cases per 100,00020,000 new cases per year in the U.S.A.death from progressive pump failure25%1-year35-40%2-year40-80%（现存活率可达70%）5-yearstabilization observed in 20-50% of patientcomplete recovery is rare
Incidence and Prognosis ◼ 3-10 cases per 100,000 ◼ 20,000 new cases per year in the U.S.A. ◼ death from progressive pump failure 1-year 25% 2-year 35-40% 5-year 40-80%（现存活率可达７０％） ◼ stabilization observed in 20-50% of patient ◼ complete recovery is rare
Idiopathic Dilated CardiomyopathyDbserved Survival of 104 Patients1201041008072605651+454037+35+312420+19·160570123468910YearsAmJCardiol1981:47:525
Idiopathic Dilated Cardiomyopathy Observed Survival of 104 Patients 104 7 2 5 6 5 1 4 5 3 7 3 5 3 1 2 4 1 9 1 6 0 2 0 4 0 6 0 8 0 100 120 0 1 2 3 4 5 6 7 8 9 1 0 Years Am J Cardiol 1981; 47:525