14.6 RecA catalyzes single- strand assimilation Paranemic joint describes a region in which two complementary sequences of DNA are associated side by side instead of being intertwined in a double helical structure. Single-strand assimilation describes the ability of RecA protein to cause a single strand of DNA to displace its homologous strand in a duplex;that is,the single strand is assimilated into the duplex. 情菜大当
Paranemic joint describes a region in which two complementary sequences of DNA are associated side by side instead of being intertwined in a double helical structure. Single-strand assimilation describes the ability of RecA protein to cause a single strand of DNA to displace its homologous strand in a duplex; that is, the single strand is assimilated into the duplex. 14.6 RecA catalyzes singlestrand assimilation
14.6 RecA catalyzes single-strand assimilation 个小八八M次 Figure 14.10 RecA promotes the assimilation of invading single strands into 清苇大当 duplex DNA so long as one of the reacting strands has a free end
Figure 14.10 RecA promotes the assimilation of invading single strands into duplex DNA so long as one of the reacting strands has a free end. 14.6 RecA catalyzes single-strand assimilation
14.6 RecA HHH出 DNA duplexes pair HHHHHHHHH catalyzes single- t进tt计HH Homologous strands are nicked strand HHHHHHHHHH assimilation Broken strands exchange between duplexes Crossover point m oves by branch migration Figure 14.2 Second nicks made in same strand Second nicks made in other strand Recombination between HHHH出 HHHHHHHHHHHH HHHHHHHHHHH two paired duplex HHHHHHHHHH DNAs could involve reciprocal single-strand HHHHHHHHHHHH Second strands Nicks are sealed cross over between HHHHHHHH exchange,branch migration,and nicking HHHHHHHHHHHH HHHHHHH 情華大当
Figure 14.2 Recombination between two paired duplex DNAs could involve reciprocal single-strand exchange, branch migration, and nicking. 14.6 RecA catalyzes singlestrand assimilation
14.6 RecA 八八N 八N八N八八 catalyzes single- ↓ Free strand initiates exchange strand assimilation 不 ↓ncmment Displaced strand Figure 14.11 RecA- mediated strand exchange between partially duplex and entirely duplex DNA generates a joint molecule H世 HHHHHHH with the same structure as a recombination Strand exchange is completed intermediate. 八八八八八N 清第大当 八八八入入
Figure 14.11 RecAmediated strand exchange between partially duplex and entirely duplex DNA generates a joint molecule with the same structure as a recombination intermediate. 14.6 RecA catalyzes singlestrand assimilation
14.6 RecA catalyzes single-strand assimilation Figure 14.12 RuvAtetramer RuvAB is an contacts all 4 strands asymmetric complex that promotes branch RuvB hexamer binds migration of as ring around DNA a Holliday Branch migration Junction. 情華大当
Figure 14.12 RuvAB is an asymmetric complex that promotes branch migration of a Holliday junction. 14.6 RecA catalyzes single-strand assimilation