Etiology.theetiologyis not clearEtiologyofcompletehydatidiformmoleEpidemiology:the morbidity of hydatidiformmole is different in different area.GTD
GTD 6 • the etiology is not clear • Etiology of complete hydatidiform mole Epidemiology: the morbidity of hydatidiform mole is different in different area. Etiology
EtiologyHigh riskfactors:1.nourishing status,social economy.2.age:over 35 and 40 years old;below 20 years old.3.hydatidiform mole history:if a patient has thehistory of 1 or 2 times hydatidiform mole,then themorbidity of the hydatidiform mole when pregnantagainis 1%and 15~20%respectively.Geneticfactors:enucleate egg fertilization:chromosome karyotypeof complete moleisdiploid90%is 46xx,10% is46XY.GTD
GTD 7 • High risk factors: 1.nourishing status,social economy. 2.age:over 35 and 40 years old;below 20 years old. 3.hydatidiform mole history:if a patient has the history of 1 or 2 times hydatidiform mole,then the morbidity of the hydatidiform mole when pregnant again is 1% and 15~20% respectively. Genetic factors: enucleate egg fertilization: chromosome karyotype of complete mole is diploid ,90% is 46XX,10% is 46XY. Etiology
EtiologyEndoreduplicationEmpty+23X23X46XXovumHomozygous23XEmpty+46XXovum23XHeterozygous23XEmpty+46XYovum23Y46YYNon-viable gamete
GTD 8 Etiology