Cervical Intraepithelial Neoplasia.CIN
Cervical Intraepithelial Neoplasia, CIN
Cervical IntraepithelialNeoplasiaCervical intraepithelial neoplasia(CiN),alsoknown as cervical dysplasia,isthe abnormalgrowth of cells on the surface of the cervixthat could potentially lead to cervicalcancer.[1] More specifically, CiN refers to thepotentially precancerous transformation ofcells of the cervix
Cervical Intraepithelial Neoplasia ❖Cervical intraepithelial neoplasia (CIN), also known as cervical dysplasia, is the abnormal growth of cells on the surface of the cervix that could potentially lead to cervical cancer.[1] More specifically, CIN refers to the potentially precancerous transformation of cells of the cervix
CIN most commonly occurs at thesquamocolumnar junction of the cervix, atransitional area between the squamousepithelium of the vagina and the columnarepithelium of the endocervix.[2]j It can alsooccur in vaginal walls and vulvar epithelium.CIN is graded on a 1-3 scale, with 3 being themost abnormal (see classification section84学时below)
CIN most commonly occurs at the squamocolumnar junction of the cervix, a transitional area between the squamous epithelium of the vagina and the columnar epithelium of the endocervix.[2] It can also occur in vaginal walls and vulvar epithelium. CIN is graded on a 1-3 scale, with 3 being the most abnormal (see classification section below) 84学时
Human papilloma virus (HPV) infection is, necessaryfor the development of CiN, but not all with thisinfection develop cervical cancer. A large number ofwomen with HPV infection never develop CIN orcervical cancer. Typically, HPV resolves on its own.However,those with anHPV infection thatlastsmore than 1 or 2 years have a higher risk ofdeveloping a higher grade of CIN.Like other intraepithelial neoplasias, CIN is notcancer and is usually curable.[3] Most cases of CINeither remainstable or are eliminated by theperson's immune system without need forintervention. However, a small percentage of casesprogress to cervical cancer, typically cervicalsquamous cell carcinoma (SCC), if left untreated
Human papilloma virus (HPV) infection is necessary for the development of CIN, but not all with this infection develop cervical cancer. A large number of women with HPV infection never develop CIN or cervical cancer. Typically, HPV resolves on its own. However, those with an HPV infection that lasts more than 1 or 2 years have a higher risk of developing a higher grade of CIN. Like other intraepithelial neoplasias, CIN is not cancer and is usually curable.[3] Most cases of CIN either remain stable or are eliminated by the person's immune system without need for intervention. However, a small percentage of cases progress to cervical cancer, typically cervical squamous cell carcinoma (SCC), if left untreated
Signs and symptomsThere are no specific symptoms of CIN alone.Generally,signs and symptoms of cervical cancerinclude:[7]abnormal or post-menopausal bleedingabnormal dischargechanges in bladder or bowel functionpelvic pain on examinationabnormal appearance or palpation of cervix.Hpv infection of the vulva and vagina can causegenital warts or be asymptomatic
Signs and symptoms There are no specific symptoms of CIN alone. Generally, signs and symptoms of cervical cancer include:[7] abnormal or post-menopausal bleeding abnormal discharge changes in bladder or bowel function pelvic pain on examination abnormal appearance or palpation of cervix. HPV infection of the vulva and vagina can cause genital warts or be asymptomatic