Differential DiagnosisHydatidiformmoleInvasivemole Placental sitetrophoblastictumorsRudimentalplacentaGTD
GTD 1 • Hydatidiform mole • Invasive mole • Placental site trophoblastic tumors • Rudimental placenta Differential Diagnosis
MetastasisLung20mldelay7kVaginaBrainLiver
GTD 2 • Lung • Vagina • Brain • Liver Metastasis
Metastasis （Lung)
GTD 3 Metastasis（Lung）
Anatomic StagingStageIdisease confined to uterusStage IIgestationaltrophoblastictumorextending outside uterus butlimited to genital structures(adnexa,vagina,broadligament)Stage III gestational trophoblasticdisease extending to lungs withor without known genital tractinvolvementStage Iv all other metastatic sitesGTD
GTD 4 Anatomic Staging Stage I disease confined to uterus Stage II gestational trophoblastic tumor extending outside uterus but limited to genital structures (adnexa, vagina, broad ligament) Stage III gestational trophoblastic disease extending to lungs with or without known genital tract involvement Stage IV all other metastatic sites
ManagementChemotherapySurgeryGID
GTD 5 • Chemotherapy • Surgery Management