上泽文通大学 Shanghai Jiao Tong University 1896 1920 1987 2006 Lecture 12-1 Microbial Genomics Chapter 12 in BROCK BIOLOGY OF MICROORGANISMS A●NV ■■■ Chen Feng School of Life Science and Technology, Shanghai Jiao Tong University http://micro.sjtu.edu.cn
1896 1920 1987 2006 Lecture 12-1 Microbial Genomics Chen Feng School of Life Science and Technology, Shanghai Jiao Tong University http://micro.sjtu.edu.cn Chapter 12 in BROCK BIOLOGY OF MICROORGANISMS
Genetic elements in bacteria Genetic elements:structures containing genetic material ·Chromosome Plasmid ·transposon Chen Feng,Lecture of Microbiology
Chen Feng, Lecture of Microbiology Genetic elements in bacteria Genetic elements: structures containing genetic material • Chromosome • Plasmid • transposon
I.Genomes and Genomics 11.1 Introduction to Genomics Genome Entire complement of genetic information Includes genes,regulatory sequences,and noncoding DNA 圈Genomics o Discipline of mapping,sequencing,analyzing,and comparing genomes Chen Feng,Lecture of Microbiology
Chen Feng, Lecture of Microbiology 11.1 Introduction to Genomics Genome • Entire complement of genetic information • Includes genes, regulatory sequences, and noncoding DNA Genomics • Discipline of mapping, sequencing, analyzing, and comparing genomes I. Genomes and Genomics
Genomics基因组学 Genomics is the study of the molecular organization of genomes,their information content,and the gene products they encode. Genomics can divided into at least three areas: Structural genomics:is the study of the physical nature of genomes.结构基因组学 Functional genomics:is concerned with the way in which the genome functions.功能基因组学 Comparative genomics:genomes from different organisms are compared to look for significant differences and similarities.比较基因组学 Chen Feng,Lecture of Microbiology
Chen Feng, Lecture of Microbiology Genomics基因组学 Genomics : is the study of the molecular organization of genomes, their information content, and the gene products they encode. Genomics can divided into at least three areas: Structural genomics: is the study of the physical nature of genomes. 结构基因组学 Functional genomics: is concerned with the way in which the genome functions. 功能基因组学 Comparative genomics: genomes from different organisms are compared to look for significant differences and similarities.比较基因组学
11.1 Introduction to Genomics >2,000 prokaryotic genomes sequenced or in progress RNA virus MS2 ·First genome sequenced in1976第一个被测出全基因 组的物种 ·3,569bp Haemophilus influenza流感嗜血杆菌 ·First cellular genome sequenced in1995第一个被测 出全基因组的细胞生物 ·1,830,137bp Chen Feng,Lecture of Microbiology
Chen Feng, Lecture of Microbiology 11.1 Introduction to Genomics >2,000 prokaryotic genomes sequenced or in progress RNA virus MS2 • First genome sequenced in 1976 第一个被测出全基因 组的物种 • 3,569 bp Haemophilus influenza流感嗜血杆菌 • First cellular genome sequenced in 1995 第一个被测 出全基因组的细胞生物 • 1,830,137 bp