Omeprazole Pharmacokinetics:T%=1 h,metabolized by CYP2C19; it's effect lasts for about 24 hours. Side effects:Generally safe.About 1%-5%of patients develop diarrhea,headache and abdominal pain
Omeprazole Pharmacokinetics: T ½ = 1 h, metabolized by CYP2C19; it’s effect lasts for about 24 hours. Side effects: Generally safe. About 1% - 5% of patients develop diarrhea, headache and abdominal pain
Other Proton Pump Inhibitor 兰索拉唑Lansoprazole H 泮托拉唑Pantoprazole H 雷贝拉唑Rabeprazole 埃索美拉唑Esomeprazole
兰索拉唑 Lansoprazole Other Proton Pump Inhibitor 泮托拉唑 Pantoprazole 雷贝拉唑 Rabeprazole 埃索美拉唑 Esomeprazole
Pirenzepine(M receptor blocker) 哌仑西平 Pirenzepine is used in the treatment of peptic ulcers,as it reduces gastric acid secretion and reduces muscle spasm.It is in a class of drugs known as muscarinic receptor antagonists. Acetylcholine is the neurotransmitter of the parasympathetic nervous system which initiates the rest-and-digest state (as opposed to fight-or-flight),the result being an increase in gastric motility and digestion. It has no effects on the brain as it cannot diffuse through the blood-brain barrier
Pirenzepine (M receptor blocker) 哌仑西平 Pirenzepine is used in the treatment of peptic ulcers, as it reduces gastric acid secretion and reduces muscle spasm. It is in a class of drugs known as muscarinic receptor antagonists. Acetylcholine is the neurotransmitter of the parasympathetic nervous system which initiates the rest-and-digest state (as opposed to fight-or-flight), the result being an increase in gastric motility and digestion. It has no effects on the brain as it cannot diffuse through the blood-brain barrier
Mucosal Protective Drugs 粘膜保护药
Mucosal Protective Drugs 粘膜保护药
Misoprostol 米索前列醇 Agonist for the EP3 receptor Misoprostol is a drug that is used for the prevention of non steroidal anti inflammatory drug(NSAID)induced gastric ulcers.It acts upon gastric parietal cells,inhibiting the secretion of gastric acid via G protein-coupled receptor mediated inhibition of adenylate cyclase,which leads to decreased intracellular cAMP levels and decreased proton pump activity at the apical surface of the parietal cell. Misoprostol also promotes mucus and bicarbonate secretion from epithelial cells,which protects gastric lumen surface
Misoprostol 米索前列醇 Misoprostol is a drug that is used for the prevention of non steroidal anti inflammatory drug (NSAID) induced gastric ulcers. It acts upon gastric parietal cells, inhibiting the secretion of gastric acid via G protein-coupled receptor mediated inhibition of adenylate cyclase, which leads to decreased intracellular cAMP levels and decreased proton pump activity at the apical surface of the parietal cell. Misoprostol also promotes mucus and bicarbonate secretion from epithelial cells, which protects gastric lumen surface. Agonist for the EP3 receptor