1CELLSOFTHEIMMUNESYSTEM1.1 PhagocytesFIGURE1Morphologyof mononuclearphagocytesA.Light micrograph of a monocyte in a peripheral blood smearB.Electronmicrograph ofaperipheral blood monocyteC.Electron micrograph of an activated tissuemacrophage
1 CELLS OF THE IMMUNE SYSTEM FIGURE 1 Morphology of mononuclear phagocytes 1.1 Phagocytes A. Light micrograph of a monocyte in a peripheral blood smear B. Electron micrograph of a peripheral blood monocyte C. Electron micrograph of an activated tissue macrophage
1CELLSOFTHEIMMUNESYSTEM1.3Antigen-PresentingCellsTissuePre-classicalDCBonemarrowMonocytelHematopoieticdendritic cellstemcellprecursorClassicalDCPlasmacytoidDCCommondendriticcellprecursorPlasmacytoidDCMonocyteFetal hemapoietic organs(yolksac,liver)InflammatoryDCHematopoieticEmbryonic tissueSkinstemcellprecursorLangerhanscellFIGURE4Maturationofdendriticcells
1 CELLS OF THE IMMUNE SYSTEM FIGURE 4 Maturation of dendritic cells 1.3 Antigen-Presenting Cells
1CELLSOFTHEIMMUNESYSTEM1.4 LymphocytesGenerativeBlood,PeripherallymphoidorganslymphlymphoidorgansMaturenaiveBlymphocytesyRecirculationBCommonlymphoidlymphocyteLymphprecursorlineagenodesBonemarrowImmature人SpleenBlymphocytesMucosalandTcutaneouslymphocytelymphoidlineagetissuesNaiveThymusTlymphocytesRecirculationNaiveTlymphocytesFIGURE5Maturationoflymphocytes
1 CELLS OF THE IMMUNE SYSTEM FIGURE 5 Maturation of lymphocytes 1.4 Lymphocytes
1CELLSOFTHEIMMUNESYSTEM1.4 LymphocytesNaiveBcellsEntryofinfectiousNaiveagentsand/orTcellsenvironmentalMucosa/antigensskinSecondary (peripheral)000lymphoidorgans1CollectionofantigensfromtissuesvialymphLymphnodeActivationoflymphocytesandAntigens/initiation ofadaptivemicrobes如年immuneresponsesCollection界ofantigensYSpleenviabloodEffectorTlymphocytesMigrationofeffectorandantibodiescells,andblooddeliveryof antibodiesto siteof infectionFIGURE6Stepsinlymphocyteactivation
1 CELLS OF THE IMMUNE SYSTEM FIGURE 6 Steps in lymphocyte activation 1.4 Lymphocytes
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