Log cfu ●●● (number of bacteria ●●●● ●●●●● ●●●● 108 ●●0●● antimicrobial ●●●0 agent agents 106 Bacteriostatic 109 Bactericidal 102 7 Time (arbitrary units)
agents
●●● 抗生素敏感性测试 ●●●● ●●●●● ●●●● ●●0●● A, Dilution test ●●●0 Antimicrobial drug concentrations lug/ml) No visible growth 64 IC= 4 ug/ml B. Agar test MBC e 32 Agar plate 7.最低抑菌浓度 Minimum inhibitory concentration(Mc) 在体外药物与细菌培养18-24小时后能抑制培养基内病原菌生长的最低药物浓度 8.最低杀菌浓度 Minimum bactericidal concentration(MBc):99.9% decrease in growth over 24 hours 24小时后能够杀灭培养基内细菌或使细菌数减少999%的最低药物浓度
抗生素敏感性测试 7. 最低抑菌浓度 Minimum inhibitory concentration (MIC)： 在体外药物与细菌培养18-24小时后能抑制培养基内病原菌生长的最低药物浓度 8. 最低杀菌浓度 Minimum bactericidal concentration (MBC): 99.9% decrease in growth over 24 hours 24小时后能够杀灭培养基内细菌或使细菌数减少99.9%的最低药物浓度