32.The mechanism of digoxin toxicity is A.enhancement of cardiac ribosome function in protein synthesis B.enhancement of muscarine endplate receptor function in the heart C.inhibition of acetylchol inesterase D.enhancement of adenylate cyclase E.inhibition of Na+,K+ATPase 33.Cardiac glycosides can not be used for treatment of 】 A.congestive heart failure B.atrial fibrillation C.atrial flutter D.paroxymal supraventricular tachycardia E.ventricular tachycardia 34.A major pharmacological mechanisms of Amrinone is inhibition of 【 】 A.HMG-CoA reductase B.ACE C.muscarinic R D.B,R E.PDE III 35.Which one of the following action can hydrochlorothiazide produce 【 】 A.hyperuricemia B.hyperkalemia C.hypocalcemia D.blood pressure increase E.hypoglycemia in diabetes patient 36.Correct statements about spironolactone is that 】 A.It is indicated in the presence of hyperkalemia B.It can not interfere with the functions of sex hormones C.It can not produce CNS side effects D.It interferes with aldosterone synthesis E.It can antagonize aldosterone receptor 37.Side effects associated with furosemide include 】 A.hyperuricemia B.metabolic alkalosis C.fluid and electrolyte imbalance D.hyponatremia E.all descriptions above are correct 38.Which of the following agents is not used for treatment of variant angina 【 】 A.nitroglycerin B.veraparmil C.propranolol D.isosorbide dinitrate E.isosorbide mononitrate 39.Which substance involves in the mechanism of antianginal function of nitroglycerin【 6
6 32.The mechanism of digoxin toxicity is【 】 A.enhancement of cardiac ribosome function in protein synthesis B.enhancement of muscarine endplate receptor function in the heart C.inhibition of acetylcholinesterase D.enhancement of adenylate cyclase E.inhibition of Na+, K+ ATPase 33.Cardiac glycosides can not be used for treatment of 【 】 A.congestive heart failure B.atrial fibrillation C.atrial flutter D.paroxymal supraventricular tachycardia E.ventricular tachycardia 34.A major pharmacological mechanisms of Amrinone is inhibition of 【 】 A.HMG-CoA reductase B.ACE C.muscarinic R D.β1 R E.PDE III 35.Which one of the following action can hydrochlorothiazide produce 【 】 A.hyperuricemia B.hyperkalemia C.hypocalcemia D.blood pressure increase E.hypoglycemia in diabetes patient 36.Correct statements about spironolactone is that 【 】 A.It is indicated in the presence of hyperkalemia B.It can not interfere with the functions of sex hormones C.It can not produce CNS side effects D.It interferes with aldosterone synthesis E.It can antagonize aldosterone receptor 37.Side effects associated with furosemide include【 】 A.hyperuricemia B.metabolic alkalosis C.fluid and electrolyte imbalance D.hyponatremia E.all descriptions above are correct 38.Which of the following agents is not used for treatment of variant angina 【 】 A.nitroglycerin B.veraparmil C.propranolol D.isosorbide dinitrate E.isosorbide mononitrate 39.Which substance involves in the mechanism of antianginal function of nitroglycerin【 】
A.carbon monoxide B.nitric oxide C.Y-GABA D.TXA2 E.substance P 40.The good candidate for treatment of hiccup is 】 A.lithium carbonate B.haloperidol C.norepinephrine D.atropine E.fluoxetine 41.Which statement is true about vitamin K 】 A.Vitamin K,and Ka do not need the help of bile salts for absorption B.Vitamin K,is synthesized by intestinal bacteria C.Vitamin K is required for the synthesis of clotting factors in the liver D.Deficiency of vitamin K in a normal diet is common. E.Vitamin K may be used to prevent urgent bleeding. 42.Which of the following may increase iron absorption[ 1 A.Vitamin CB.NaHCO,C.Tannic acid D.Phosphorus and calcium E.Tetracyclines 43.What drug can be used to treat bleeding caused by Urokinase 】 A.Vitamin K B.Protamine sulfate C.Aminocaproic acid D.Ferrous sulfate E.Folic acid 44.Megaloblastic anemia caused by dihydrofolate reductase inhibitor should use 【 】 A.VitBia B.Leucovorin C.Ferrous sulfate D.Iron dextran E.Folic acid 45.A long-acting glucocorticoid is 】 A.dexamethasone B.hydrocortisone C.cortisol D.methylprednisolone E.prednisone 46.Which of the fol lowing is not an action of glucocorticoids[ 】 A.Immunosuppressive B.Anti-inflammatory C.Increase of red blood cells D.Nervous system excitatio E.Increase of lymphocyte 47.Result of abrupt withdrawal of corticosteroid after treatment usually is 【 A.adrenal insufficiency B.hyperactivity of the adrenal cortex C.an adrenal cortex with decrease response to ACTH D.A and C E.all of the bove 48.Cortisol can produce following effects EXCEPT 7
7 A.carbon monoxide B.nitric oxide C.γ-GABA D.TXA2 E.substance P 40.The good candidate for treatment of hiccup is 【 】 A.lithium carbonate B.haloperidol C.norepinephrine D.atropine E.fluoxetine 41.Which statement is true about vitamin K 【 】 A.Vitamin K1 and K2 do not need the help of bile salts for absorption B.Vitamin K3 is synthesized by intestinal bacteria C.Vitamin K is required for the synthesis of clotting factors in the liver D.Deficiency of vitamin K in a normal diet is common. E.Vitamin K may be used to prevent urgent bleeding. 42.Which of the following may increase iron absorption 【 】 A.Vitamin C B.NaHCO3 C.Tannic acid D.Phosphorus and calcium E.Tetracyclines 43.What drug can be used to treat bleeding caused by Urokinase 【 】 A.Vitamin K B.Protamine sulfate C.Aminocaproic acid D.Ferrous sulfate E.Folic acid 44.Megaloblastic anemia caused by dihydrofolate reductase inhibitor should use 【 】 A.VitB12 B.Leucovorin C.Ferrous sulfate D.Iron dextran E.Folic acid 45.A long-acting glucocorticoid is 【 】 A.dexamethasone B.hydrocortisone C.cortisol D.methylprednisolone E.prednisone 46.Which of the following is not an action of glucocorticoids 【 】 A.Immunosuppressive B.Anti-inflammatory C.Increase of red blood cells D.Nervous system excitatio E.Increase of lymphocyte 47.Result of abrupt withdrawal of corticosteroid after treatment usually is 【 】 A.adrenal insufficiency B.hyperactivity of the adrenal cortex C.an adrenal cortex with decrease response to ACTH D. A and C E.all of the bove 48.Cortisol can produce following effects EXCEPT 【 】