消化性溃疡 Peptic ulcer 刘纯伦 重庆医科大学附属第一医院消化内科
1 消化性溃疡 Peptic ulcer 刘 纯 伦 重庆医科大学附属第一医院消化内科
一、概述 是一种发生在消化道的慢性溃疡,因其形成与胃酸和 胃蛋白酶的自身消化作用有关而得名。 主要发生在胃和十二指肠,也可发生在食道的下段, 十二指肠降段、水平段、升端,Meckel憩室(具有功能 性胃腺)以及胃肠吻合术后毗邻的小肠。 以胃溃疡(gastric ulcer,.GU)和十二指肠溃疡 (duodenal ulcer,DU常见
2 一、概述 是一种发生在消化道的慢性溃疡,因其形成与胃酸和 胃蛋白酶的自身消化作用有关而得名。 主要发生在胃和十二指肠,也可发生在食道的下段, 十二指肠降段、水平段、升端,Meckel憩室(具有功能 性胃腺)以及胃肠吻合术后毗邻的小肠。 以胃溃疡(gastric ulcer,GU)和十二指肠溃疡 (duodenal ulcer,DU)常见
溃疡与糜烂的区别: 溃疡:粘膜缺损超过粘膜肌层 糜烂:粘膜缺损不超过粘膜肌层 2 a 器0 Y品 Comment:
3 溃疡与糜烂的区别: 溃疡:粘膜缺损超过粘膜肌层 糜烂:粘膜缺损不超过粘膜肌层
二、流行病学 Although the incidence of peptic ulcer disease in Western Countries has declined over the past 100 years,around 1 in 10 Americans are still affected. Sonnenberg Aand Everhart JE(1996)The prevalenceof self reported peptic ulcer in the United States.Am J Public Health 86:200-205 The annual financial burden of peptic ulcer disease in the US. including direct and indirect costs,is estimated as US$3.4 billion Sandler RS et al.(2002)The burden of selecteddigestive diseases in the United States.Gastroenterology 122:1500-1511
4 ◆ Although the incidence of peptic ulcer disease in Western Countries has declined over the past 100 years, around 1 in 10 Americans are still affected. Sonnenberg A and Everhart JE (1996) The prevalenceof self reported peptic ulcer in the United States. Am J Public Health 86: 200–205 二、流行病学 ◆The annual financial burden of peptic ulcer disease in the US, including direct and indirect costs, is estimated as US$3.4 billion. Sandler RS et al. (2002) The burden of selecteddigestive diseases in the United States.Gastroenterology 122: 1500–1511
■男性好发 DU 男:女=4.46.8:1 GU 男:女=3.6~4.7:1 ■DU较GU更常见DU:GU=1.5~5.6:1 ■ 年龄特点 DU常见于中青年 GU的平均年龄较DU晚10年 季节性:秋冬和冬春之交远比夏季常见
5 男性好发 DU 男:女=4.4~6.8: 1 GU 男:女=3.6~4.7: 1 DU 较GU更常见 DU:GU=1.5~5.6:1 年龄特点 DU常见于中青年 GU的平均年龄较DU晚10年 季节性: 秋冬和冬春之交远比夏季常见