蘇北人民医院Sincethe skull cannotexpand inresponsetothegrowthofatumor,thefirstsymptomsareusuallydueto increased pressure in thebrain.·Headaches·Seizures·Memoryloss·Changes in behavior·Loss in movement orsensation on one side of the body·Languagedysfunction and cognitiveimpairmentsOthersymptomsmayalsooccurdependingonthesizeand location of the tumor
蘇北人民医院Glioblastoma（GBM）
蘇北人民医院High-gradeGliomasGlioblastomamultiforme(GBM):isamalignantqliomaGBM is themostaggressiveandmostcommonprimarybraintumor.Glioblastomamultiformeusuallyspreadsquicklyandinvadesotherpartsofthebrain,withtentaclelikeprojections,makingcompletesurgicalremovalmoredifficult
Pathological Classificationglioblastomamultiforme(GBM)anaplasticastrocytoma(AA)anaplasticoligodendroglioma(AO)·anaplastic oligoastrocytomaor"mixed"gliomagliosarcomagemistocyticastrocytoma(GA)蘇北人民医院
蘇北人民医院DIAGNOSIS·DiagnosticImaging·MRlorCT scanwithcontrast dyethatmakestheborderand detailsofthetumormorevisible·On MRI with contrast,highgrade gliomasshowbrightly(thisiscalledenhancement);lowgradegliomasfrequently do notenhancewith contrast,orslightlyenhance·the examination of a patient's tumor tissue underamicroscopeandmolecularanalysiscanconrmanexactdiagnosis